TADB
TA Pair: RHH-PIN
#OrganismToxinAntitoxinLocus IDReplicon
1Acaryochloris marina MBIC110174622 AM1_0688AM1_0687NC_009925
2Acaryochloris marina MBIC110174635 AM1_4808AM1_4807NC_009925
3Acaryochloris marina MBIC110174621 AM1_0686AM1_0685NC_009925
4Acidiphilium cryptum JF-53906 Acry_3180Acry_3181NC_009467
5Acidiphilium cryptum JF-53908 Acry_3268Acry_3269NC_009467
6Acidiphilium cryptum JF-53913 Acry_3511Acry_3512NC_009469
7Acidithiobacillus ferrooxidans ATCC 539936005 Lferr_1456Lferr_1455NC_011206
8Acidithiobacillus ferrooxidans ATCC 539935992 Lferr_0229Lferr_0230NC_011206
9Acidithiobacillus ferrooxidans ATCC 539936001 Lferr_1289Lferr_1290NC_011206
10Acidovorax citrulli AAC00-13307 Aave_1030Aave_1029NC_008752
11Acidovorax sp. JS423416 Ajs_3028Ajs_3027NC_008782
12Aeropyrum pernix K14 APE_0471aAPE_0471bNC_000854
13Agrobacterium tumefaciens str. C58339 Atu1004Atu1005NC_003062
14Alkalilimnicola ehrlichii MLHE-12885 Mlg_2306Mlg_2305NC_008340
15Archaeoglobus fulgidus DSM 430453 AF1479AF1478NC_000917
16Archaeoglobus fulgidus DSM 430454 AF1480AF1481NC_000917
17Archaeoglobus fulgidus DSM 430458 AF1690AF1689NC_000917
18Archaeoglobus fulgidus DSM 430457 AF1683AF1682NC_000917
19Archaeoglobus fulgidus DSM 430460 AF1996AF1997NC_000917
20Azorhizobium caulinodans ORS 5714654 AZC_3839AZC_3840NC_009937
21Beijerinckia indica subsp. indica ATCC 90395399 Bind_3708Bind_3707NC_010580
22Beijerinckia indica subsp. indica ATCC 90395410 Bind_2795Bind_2796NC_010581
23Bifidobacterium longum DJO10A5644 BLD_0266BLD_0265NC_010816
24Bifidobacterium longum DJO10A5645 BLD_1045BLD_1044NC_010816
25Bifidobacterium longum NCC2705641 BL1399BL1398NC_004307
26Bordetella bronchiseptica RB501335 BB2471BB2472NC_002927
27Bordetella parapertussis 128221291 BPP1402BPP1403NC_002928
28Bradyrhizobium sp. BTAi13918 BBta_p0291BBta_p0292NC_009475
29Burkholderia vietnamiensis G43666 Bcep1808_6071Bcep1808_6070NC_009254
30Caldicellulosiruptor saccharolyticus DSM 89033790 Csac_1519Csac_1518NC_009437
31Caldicellulosiruptor saccharolyticus DSM 89033794 Csac_1947Csac_1948NC_009437
32Candidatus Desulforudis audaxviator MP104C5135 Daud_0983Daud_0984NC_010424
33Candidatus Desulforudis audaxviator MP104C5131 Daud_0415Daud_0414NC_010424
34Candidatus Korarchaeum cryptofilum OPF85189 Kcr_0749Kcr_0748NC_010482
35Candidatus Korarchaeum cryptofilum OPF85181 Kcr_0415Kcr_0414NC_010482
36Candidatus Korarchaeum cryptofilum OPF85182 Kcr_0454Kcr_0455NC_010482
37Candidatus Solibacter usitatus Ellin60763054 Acid_0374Acid_0373NC_008536
38Candidatus Solibacter usitatus Ellin60763097 Acid_7079Acid_7080NC_008536
39Candidatus Solibacter usitatus Ellin60763091 Acid_6371Acid_6370NC_008536
40Candidatus Solibacter usitatus Ellin60763095 Acid_7038Acid_7039NC_008536
41Candidatus Solibacter usitatus Ellin60763066 Acid_1919Acid_1920NC_008536
42Candidatus Solibacter usitatus Ellin60763085 Acid_5515Acid_5514NC_008536
43Candidatus Solibacter usitatus Ellin60763086 Acid_5574Acid_5575NC_008536
44Candidatus Solibacter usitatus Ellin60763087 Acid_5649Acid_5648NC_008536
45Cellvibrio japonicus Ueda1075752 CJA_1098CJA_1097NC_010995
46Chelativorans sp. BNC12792 Meso_4325Meso_4324NC_008242
47Chlorobium chlorochromatii CaD32134 Cag_0697Cag_0696NC_007514
48Chlorobium chlorochromatii CaD32122 Cag_0266Cag_0267NC_007514
49Chlorobium luteolum DSM 2732113 Plut_1876Plut_1877NC_007512
50Chlorobium phaeobacteroides BS15654 Cphamn1_0232Cphamn1_0231NC_010831
51Chlorobium phaeobacteroides BS15669 Cphamn1_1054Cphamn1_1055NC_010831
52Chlorobium phaeobacteroides BS15685 Cphamn1_1966Cphamn1_1965NC_010831
53Chlorobium phaeobacteroides BS15683 Cphamn1_1961Cphamn1_1962NC_010831
54Chlorobium phaeobacteroides DSM 2663191 Cpha266_1382Cpha266_1381NC_008639
55Chlorobium phaeobacteroides DSM 2663201 Cpha266_2640Cpha266_2641NC_008639
56Chloroherpeton thalassium ATCC 351105807 Ctha_2045Ctha_2044NC_011026
57Chromohalobacter salexigens DSM 30432640 Csal_1070Csal_1069NC_007963
58Citrobacter koseri ATCC BAA-8954496 CKO_03121CKO_03122NC_009792
59Coxiella burnetii RSA 3314818 COXBURSA331_A1380COXBURSA331_A1381NC_010117
60Cupriavidus metallidurans CH342646 Rmet_6032Rmet_6033NC_007971
61Cupriavidus taiwanensis LMG 194245296 RALTA_A2411RALTA_A2410NC_010528
62Cyanothece sp. ATCC 511425332 cce_2850cce_2851NC_010546
63Cyanothece sp. ATCC 511425325 cce_2143cce_2142NC_010546
64Cyanothece sp. ATCC 511425310 cce_0008cce_0007NC_010546
65Cyanothece sp. ATCC 511425307 cce_5277cce_5278NC_010541
66Deinococcus radiodurans R1139 DR_0660DR_0661NC_001263
67Delftia acidovorans SPH-14772 Daci_5522Daci_5523NC_010002
68Delftia acidovorans SPH-14773 Daci_5817Daci_5816NC_010002
69Delftia acidovorans SPH-14775 Daci_5841Daci_5842NC_010002
70Delftia acidovorans SPH-14762 Daci_2800Daci_2799NC_010002
71Desulfococcus oleovorans Hxd34673 Dole_1812Dole_1811NC_009943
72Desulfococcus oleovorans Hxd34680 Dole_2343Dole_2342NC_009943
73Desulfococcus oleovorans Hxd34675 Dole_1840Dole_1839NC_009943
74Desulfococcus oleovorans Hxd34663 Dole_0411Dole_0410NC_009943
75Desulfococcus oleovorans Hxd34687 Dole_3135Dole_3136NC_009943
76Dinoroseobacter shibae DFL 12 = DSM 164934733 Dshi_4210Dshi_4211NC_009959
77Erythrobacter litoralis HTCC25942334 ELI_02425ELI_02420NC_007722
78Frankia alni ACN14a2854 FRAAL4817FRAAL4818NC_008278
79Frankia sp. CcI32380 Francci3_1502Francci3_1501NC_007777
80Geobacter lovleyi SZ5621 Glov_0067Glov_0068NC_010814
81Geobacter lovleyi SZ5627 Glov_1224Glov_1225NC_010814
82Geobacter uraniireducens Rf43981 Gura_3164Gura_3165NC_009483
83Geobacter uraniireducens Rf43992 Gura_3867Gura_3868NC_009483
84Geobacter uraniireducens Rf43941 Gura_0946Gura_0947NC_009483
85Geobacter uraniireducens Rf43963 Gura_1751Gura_1750NC_009483
86Geobacter uraniireducens Rf43990 Gura_3863Gura_3864NC_009483
87Gloeobacter violaceus PCC 74211418 gll0844gsl0845NC_005125
88Gloeobacter violaceus PCC 74211428 gll1573gsl1574NC_005125
89Gloeobacter violaceus PCC 74211430 glr1678gsr1677NC_005125
90Gloeobacter violaceus PCC 74211433 gll1696gll1697NC_005125
91Gloeobacter violaceus PCC 74211443 gll2300gsl2301NC_005125
92Gloeobacter violaceus PCC 74211457 glr3225gsr3224NC_005125
93Gloeobacter violaceus PCC 74211417 gll0721gsl0722NC_005125
94Gloeobacter violaceus PCC 74211421 glr1124gsr1125NC_005125
95Gloeobacter violaceus PCC 74211452 gll2899gsl2900NC_005125
96Gramella forsetii KT08033138 GFO_3473GFO_3474NC_008571
97Gramella forsetii KT08033130 GFO_0859GFO_0860NC_008571
98Granulibacter bethesdensis CGDNIH12893 GbCGDNIH1_2100GbCGDNIH1_2101NC_008343
99Haloarcula marismortui ATCC 430491542 rrnAC1057rrnAC1056NC_006396
100Haloarcula marismortui ATCC 430491544 rrnAC1674rrnAC1673NC_006396
101Haloarcula marismortui ATCC 430491540 rrnAC0586rrnAC0588NC_006396
102Haloarcula marismortui ATCC 430491543 rrnAC1566rrnAC1567NC_006396
103Halobacterium salinarum R15084 OE5429ROE5431RNC_010368
104Halobacterium sp. NRC-11731 VNG7131VNG7130NC_001869
105Haloquadratum walsbyi DSM 167902780 HQ2130AHQ2131ANC_008212
106Haloquadratum walsbyi DSM 167902786 HQ3581AHQ3580ANC_008212
107Haloquadratum walsbyi DSM 167902785 HQ3577AHQ3578ANC_008212
108Haloquadratum walsbyi DSM 167902784 HQ3571AHQ3570ANC_008212
109Haloquadratum walsbyi DSM 167902781 HQ2135AHQ2134ANC_008212
110Halorhodospira halophila SL13471 Hhal_0792Hhal_0791NC_008789
111Hyperthermus butylicus DSM 54563491 Hbut_0564Hbut_0563NC_008818
112Hyperthermus butylicus DSM 54563494 Hbut_0699Hbut_0698NC_008818
113Hyperthermus butylicus DSM 54563499 Hbut_1346Hbut_1345NC_008818
114Hyperthermus butylicus DSM 54563502 Hbut_1500Hbut_1501NC_008818
115Hyperthermus butylicus DSM 54563489 Hbut_0149Hbut_0148NC_008818
116Kineococcus radiotolerans SRS30216 = ATCC BAA-1494312 Krad_2113Krad_2114NC_009664
117Klebsiella pneumoniae subsp. pneumoniae MGH 785784250 KPN_04186KPN_04185NC_009648
118Leptospira biflexa serovar Patoc strain Patoc 1 (Ames)5702 LBF_2175LBF_2174NC_010842
119Leptospira biflexa serovar Patoc strain Patoc 1 (Ames)5711 LBF_2813LBF_2814NC_010842
120Leptospira biflexa serovar Patoc strain Patoc 1 (Ames)5709 LBF_2276LBF_2275NC_010842
121Leptospira biflexa serovar Patoc strain Patoc 1 (Ames)5704 LBF_2183LBF_2182NC_010842
122Leptospira biflexa serovar Patoc strain Patoc 1 (Paris)5427 LEPBI_I2240LEPBI_I2239NC_010602
123Leptospira biflexa serovar Patoc strain Patoc 1 (Paris)5432 LEPBI_I2346LEPBI_I2345NC_010602
124Leptospira biflexa serovar Patoc strain Patoc 1 (Paris)5434 LEPBI_I2912LEPBI_I2913NC_010602
125Leptospira biflexa serovar Patoc strain Patoc 1 (Paris)5429 LEPBI_I2248LEPBI_I2247NC_010602
126Leptospira borgpetersenii serovar Hardjo-bovis str. JB1973023 LBJ_0624LBJ_0623NC_008510
127Leptospira borgpetersenii serovar Hardjo-bovis str. JB1973025 LBJ_2077LBJ_2076NC_008510
128Leptospira borgpetersenii serovar Hardjo-bovis str. L5503018 LBL_0973LBL_0974NC_008508
129Leptospira borgpetersenii serovar Hardjo-bovis str. L5503020 LBL_2455LBL_2456NC_008508
130Leptospira interrogans serovar Copenhageni str. Fiocruz L1-1301514 LIC10866LIC10867NC_005823
131Leptospira interrogans serovar Copenhageni str. Fiocruz L1-1301517 LIC12116LIC12117NC_005823
132Leptospira interrogans serovar Lai str. 56601656 LA_3274LA_3275NC_004342
133Leptothrix cholodnii SP-65270 Lcho_0630Lcho_0631NC_010524
134Leptothrix cholodnii SP-65284 Lcho_4334Lcho_4335NC_010524
135Magnetococcus marinus MC-13155 Mmc1_2883Mmc1_2884NC_008576
136Maricaulis maris MCS102944 Mmar10_0806Mmar10_0805NC_008347
137Mesorhizobium loti MAFF303099218 mll5078msl5079NC_002678
138Mesorhizobium loti MAFF3030991745 mll9357msl9358NC_002679
139Metallosphaera sedula DSM 53483818 Msed_0411Msed_0412NC_009440
140Metallosphaera sedula DSM 53483817 Msed_0338Msed_0339NC_009440
141Metallosphaera sedula DSM 53483830 Msed_1385Msed_1386NC_009440
142Metallosphaera sedula DSM 53483826 Msed_1214Msed_1215NC_009440
143Metallosphaera sedula DSM 53483822 Msed_0908Msed_0909NC_009440
144Metallosphaera sedula DSM 53483821 Msed_0899Msed_0898NC_009440
145Methanocaldococcus jannaschii DSM 266120 MJ_1121MJ_1122NC_000909
146Methanocaldococcus jannaschii DSM 266126 MJ_1680MJ_1679NC_000909
147Methanoculleus marisnigri JR13558 Memar_1702Memar_1701NC_009051
148Methanoregula boonei 6A84378 Mboo_0985Mboo_0984NC_009712
149Methanosarcina acetivorans C2A808 MA1515MA1514NC_003552
150Methanospirillum hungatei JF-12442 Mhun_1454Mhun_1455NC_007796
151Methylobacterium extorquens PA14870 Mext_0004Mext_0005NC_010172
152Methylobacterium populi BJ0015554 Mpop_1379Mpop_1378NC_010725
153Methylobacterium populi BJ0015547 Mpop_0728Mpop_0727NC_010725
154Methylobacterium populi BJ0015555 Mpop_1406Mpop_1405NC_010725
155Methylobacterium radiotolerans JCM 28315217 Mrad2831_1130Mrad2831_1129NC_010505
156Methylobacterium radiotolerans JCM 28315219 Mrad2831_1871Mrad2831_1870NC_010505
157Microcystis aeruginosa NIES-8435000 MAE_37970MAE_37980NC_010296
158Microcystis aeruginosa NIES-8434987 MAE_32540MAE_32550NC_010296
159Microcystis aeruginosa NIES-8434988 MAE_32560MAE_32550NC_010296
160Microcystis aeruginosa NIES-8434941 MAE_07680MAE_07670NC_010296
161Microcystis aeruginosa NIES-8434955 MAE_13550MAE_13540NC_010296
162Microcystis aeruginosa NIES-8434964 MAE_17540MAE_17530NC_010296
163Moorella thermoacetica ATCC 390732271 Moth_0176Moth_0175NC_007644
164Moorella thermoacetica ATCC 390732291 Moth_2011Moth_2012NC_007644
165Moorella thermoacetica ATCC 390732289 Moth_1768Moth_1769NC_007644
166Mycobacterium avium 1043163 MAV_1240MAV_1239NC_008595
167Mycobacterium bovis AF2122/971124 Mb0564cMb0565cNC_002945
168Mycobacterium bovis AF2122/971123 Mb0309Mb0308NC_002945
169Mycobacterium bovis AF2122/971166 Mb2780cMb2781cNC_002945
170Mycobacterium bovis AF2122/971160 Mb2576Mb2575NC_002945
171Mycobacterium bovis AF2122/971161 Mb2578Mb2577NC_002945
172Mycobacterium bovis AF2122/971162 Mb2579cMb2580cNC_002945
173Mycobacterium bovis AF2122/971164 Mb2634Mb2633NC_002945
174Mycobacterium bovis AF2122/971165 Mb2778cMb2779cNC_002945
175Mycobacterium bovis AF2122/971121 Mb0246Mb0245NC_002945
176Mycobacterium bovis AF2122/971169 Mb2897Mb2896NC_002945
177Mycobacterium bovis AF2122/971173 Mb3349cMb3350cNC_002945
178Mycobacterium bovis AF2122/971159 Mb2559cMb2559AcNC_002945
179Mycobacterium bovis AF2122/971158 Mb2556Mb2555NC_002945
180Mycobacterium bovis AF2122/971157 Mb2522Mb2521NC_002945
181Mycobacterium bovis AF2122/971156 Mb2129cMb2130cNC_002945
182Mycobacterium bovis AF2122/971152 Mb2033Mb2032NC_002945
183Mycobacterium bovis AF2122/971148 Mb1988Mb1987NC_002945
184Mycobacterium bovis AF2122/971146 Mb1869cMb1870cNC_002945
185Mycobacterium bovis AF2122/971145 Mb1770Mb1769NC_002945
186Mycobacterium bovis AF2122/971144 Mb1749cMb1750cNC_002945
187Mycobacterium bovis AF2122/971143 Mb1587Mb1586NC_002945
188Mycobacterium bovis AF2122/971141 Mb1432cMb1433cNC_002945
189Mycobacterium bovis AF2122/971139 Mb1274Mb1273NC_002945
190Mycobacterium bovis AF2122/971138 Mb1144Mb1143NC_002945
191Mycobacterium bovis AF2122/971135 Mb0770Mb0769NC_002945
192Mycobacterium bovis AF2122/971133 Mb0680cMb0681cNC_002945
193Mycobacterium bovis AF2122/971131 Mb0675cMb0676cNC_002945
194Mycobacterium bovis AF2122/971129 Mb0640Mb0639NC_002945
195Mycobacterium bovis AF2122/971128 Mb0625Mb0624NC_002945
196Mycobacterium bovis AF2122/971125 Mb0597Mb0596NC_002945
197Mycobacterium bovis BCG str. Pasteur 1173P23363 BCG_2122cBCG_2123cNC_008769
198Mycobacterium bovis BCG str. Pasteur 1173P23384 BCG_3756cBCG_3756ANC_008769
199Mycobacterium bovis BCG str. Pasteur 1173P23380 BCG_3386cBCG_3387cNC_008769
200Mycobacterium bovis BCG str. Pasteur 1173P23376 BCG_2894BCG_2893NC_008769
201Mycobacterium bovis BCG str. Pasteur 1173P23373 BCG_2775cBCG_2776cNC_008769
202Mycobacterium bovis BCG str. Pasteur 1173P23372 BCG_2773cBCG_2774cNC_008769
203Mycobacterium bovis BCG str. Pasteur 1173P23371 BCG_2627BCG_2626NC_008769
204Mycobacterium bovis BCG str. Pasteur 1173P23369 BCG_2572cBCG_2573cNC_008769
205Mycobacterium bovis BCG str. Pasteur 1173P23368 BCG_2571BCG_2570NC_008769
206Mycobacterium bovis BCG str. Pasteur 1173P23367 BCG_2569BCG_2568NC_008769
207Mycobacterium bovis BCG str. Pasteur 1173P23366 BCG_2551cBCG_2552cNC_008769
208Mycobacterium bovis BCG str. Pasteur 1173P23365 BCG_2548BCG_2547NC_008769
209Mycobacterium bovis BCG str. Pasteur 1173P23364 BCG_2514BCG_2513NC_008769
210Mycobacterium bovis BCG str. Pasteur 1173P23359 BCG_2027BCG_2026NC_008769
211Mycobacterium bovis BCG str. Pasteur 1173P23354 BCG_1992BCG_1991NC_008769
212Mycobacterium bovis BCG str. Pasteur 1173P23353 BCG_1873cBCG_1874cNC_008769
213Mycobacterium bovis BCG str. Pasteur 1173P23352 BCG_1780BCG_1779NC_008769
214Mycobacterium bovis BCG str. Pasteur 1173P23351 BCG_1759cBCG_1760cNC_008769
215Mycobacterium bovis BCG str. Pasteur 1173P23350 BCG_1613BCG_1612NC_008769
216Mycobacterium bovis BCG str. Pasteur 1173P23349 BCG_1458cBCG_1459cNC_008769
217Mycobacterium bovis BCG str. Pasteur 1173P23347 BCG_1302BCG_1301NC_008769
218Mycobacterium bovis BCG str. Pasteur 1173P23346 BCG_1174BCG_1173NC_008769
219Mycobacterium bovis BCG str. Pasteur 1173P23344 BCG_0799BCG_0798NC_008769
220Mycobacterium bovis BCG str. Pasteur 1173P23343 BCG_0710cBCG_0711cNC_008769
221Mycobacterium bovis BCG str. Pasteur 1173P23341 BCG_0705cBCG_0706cNC_008769
222Mycobacterium bovis BCG str. Pasteur 1173P23339 BCG_0670BCG_0669NC_008769
223Mycobacterium bovis BCG str. Pasteur 1173P23338 BCG_0664BCG_0663ANC_008769
224Mycobacterium bovis BCG str. Pasteur 1173P23337 BCG_0655BCG_0654NC_008769
225Mycobacterium bovis BCG str. Pasteur 1173P23334 BCG_0627BCG_0626NC_008769
226Mycobacterium bovis BCG str. Pasteur 1173P23333 BCG_0594cBCG_0595cNC_008769
227Mycobacterium bovis BCG str. Pasteur 1173P23332 BCG_0341BCG_0340NC_008769
228Mycobacterium bovis BCG str. Pasteur 1173P23330 BCG_0315cBCG_0315ANC_008769
229Mycobacterium bovis BCG str. Pasteur 1173P23329 BCG_0278BCG_0277NC_008769
230Mycobacterium bovis BCG str. Pasteur 1173P23328 BCG_0096BCG_0095ANC_008769
231Mycobacterium gilvum PYR-GCK3684 Mflv_0928Mflv_0929NC_009338
232Mycobacterium smegmatis str. MC2 1553165 experimental MSMEG_1284MSMEG_1283NC_008596
233Mycobacterium sp. KMS3259 Mkms_5559Mkms_5560NC_008703
234Mycobacterium sp. KMS3262 Mkms_5903Mkms_5902NC_008704
235Mycobacterium sp. MCS2754 Mmcs_5502Mmcs_5501NC_008147
236Mycobacterium tuberculosis CDC1551278 MT2622MT2621NC_002755
237Mycobacterium tuberculosis CDC1551277 MT2605MT2606NC_002755
238Mycobacterium tuberculosis CDC1551276 MT2602MT2601.2NC_002755
239Mycobacterium tuberculosis CDC1551275 MT2569MT2568NC_002755
240Mycobacterium tuberculosis CDC1551273 MT2163MT2164NC_002755
241Mycobacterium tuberculosis CDC1551288 MT3421MT3422NC_002755
242Mycobacterium tuberculosis CDC1551265 MT2034MT2035NC_002755
243Mycobacterium tuberculosis CDC1551261 MT2003MT2002NC_002755
244Mycobacterium tuberculosis CDC1551260 MT1886MT1887NC_002755
245Mycobacterium tuberculosis CDC1551259 MT1783MT1782NC_002755
246Mycobacterium tuberculosis CDC1551258 MT1761MT1762NC_002755
247Mycobacterium tuberculosis CDC1551257 MT1612MT1611NC_002755
248Mycobacterium tuberculosis CDC1551255 MT1441MT1442NC_002755
249Mycobacterium tuberculosis CDC1551254 MT1280MT1279NC_002755
250Mycobacterium tuberculosis CDC1551268 MT2065MT2064.1NC_002755
251Mycobacterium tuberculosis CDC1551283 MT2829MT2830NC_002755
252Mycobacterium tuberculosis CDC1551282 MT2827MT2828NC_002755
253Mycobacterium tuberculosis CDC1551280 MT2677MT2676NC_002755
254Mycobacterium tuberculosis CDC1551279 MT2624MT2623NC_002755
255Mycobacterium tuberculosis CDC1551237 MT0254MT0253NC_002755
256Mycobacterium tuberculosis CDC1551238 MT0289MT0290NC_002755
257Mycobacterium tuberculosis CDC1551239 MT0574MT0575NC_002755
258Mycobacterium tuberculosis CDC1551242 MT0638MT0637NC_002755
259Mycobacterium tuberculosis CDC1551243 MT0646MT0645.2NC_002755
260Mycobacterium tuberculosis CDC1551244 MT0652MT0651NC_002755
261Mycobacterium tuberculosis CDC1551245 MT0685MT0686NC_002755
262Mycobacterium tuberculosis CDC1551247 MT0690MT0691NC_002755
263Mycobacterium tuberculosis CDC1551249 MT0773MT0772.6NC_002755
264Mycobacterium tuberculosis CDC1551253 MT1144MT1143.1NC_002755
265Mycobacterium tuberculosis CDC1551292 MT3799MT3800NC_002755
266Mycobacterium tuberculosis F114157 TBFG_11426TBFG_11427NC_009565
267Mycobacterium tuberculosis F114158 TBFG_11593TBFG_11592NC_009565
268Mycobacterium tuberculosis F114172 TBFG_12570TBFG_12571NC_009565
269Mycobacterium tuberculosis F114169 TBFG_12137TBFG_12138NC_009565
270Mycobacterium tuberculosis F114174 TBFG_12772TBFG_12773NC_009565
271Mycobacterium tuberculosis F114173 TBFG_12770TBFG_12771NC_009565
272Mycobacterium tuberculosis F114170 TBFG_12566TBFG_12565NC_009565
273Mycobacterium tuberculosis F114171 TBFG_12568TBFG_12567NC_009565
274Mycobacterium tuberculosis F114159 TBFG_11759TBFG_11758NC_009565
275Mycobacterium tuberculosis F114160 TBFG_11982TBFG_11981NC_009565
276Mycobacterium tuberculosis F114165 TBFG_12042TBFG_12041NC_009565
277Mycobacterium tuberculosis F114140 TBFG_10243TBFG_10242NC_009565
278Mycobacterium tuberculosis F114141 TBFG_10281TBFG_10282NC_009565
279Mycobacterium tuberculosis F114143 TBFG_10593TBFG_10592NC_009565
280Mycobacterium tuberculosis F114182 TBFG_13351TBFG_13352NC_009565
281Mycobacterium tuberculosis F114146 TBFG_10620TBFG_10619NC_009565
282Mycobacterium tuberculosis F114147 TBFG_10635TBFG_10634NC_009565
283Mycobacterium tuberculosis F114149 TBFG_10669TBFG_10670NC_009565
284Mycobacterium tuberculosis F114151 TBFG_10674TBFG_10675NC_009565
285Mycobacterium tuberculosis F114152 TBFG_10763TBFG_10762NC_009565
286Mycobacterium tuberculosis F114154 TBFG_11136TBFG_11135NC_009565
287Mycobacterium tuberculosis F114155 TBFG_11267TBFG_11266NC_009565
288Mycobacterium tuberculosis H37Ra4101 MRA_1406MRA_1407NC_009525
289Mycobacterium tuberculosis H37Ra4083 MRA_0249MRA_0248NC_009525
290Mycobacterium tuberculosis H37Ra4084 MRA_0285MRA_0286NC_009525
291Mycobacterium tuberculosis H37Ra4086 MRA_0310MRA_0309NC_009525
292Mycobacterium tuberculosis H37Ra4087 MRA_0556MRA_0557NC_009525
293Mycobacterium tuberculosis H37Ra4090 MRA_0616MRA_0615NC_009525
294Mycobacterium tuberculosis H37Ra4091 MRA_0633MRA_0632NC_009525
295Mycobacterium tuberculosis H37Ra4093 MRA_0667MRA_0667ANC_009525
296Mycobacterium tuberculosis H37Ra4095 MRA_0671MRA_0672NC_009525
297Mycobacterium tuberculosis H37Ra4096 MRA_0757MRA_0756NC_009525
298Mycobacterium tuberculosis H37Ra4098 MRA_1124MRA_1123ANC_009525
299Mycobacterium tuberculosis H37Ra4099 MRA_1251MRA_1250NC_009525
300Mycobacterium tuberculosis H37Ra4102 MRA_1573MRA_1572NC_009525
301Mycobacterium tuberculosis H37Ra4103 MRA_1730MRA_1731NC_009525
302Mycobacterium tuberculosis H37Ra4104 MRA_1752MRA_1751NC_009525
303Mycobacterium tuberculosis H37Ra4105 MRA_1849MRA_1850NC_009525
304Mycobacterium tuberculosis H37Ra4106 MRA_1963MRA_1962NC_009525
305Mycobacterium tuberculosis H37Ra4110 MRA_1993MRA_1994NC_009525
306Mycobacterium tuberculosis H37Ra4113 MRA_2026MRA_2025NC_009525
307Mycobacterium tuberculosis H37Ra4118 MRA_2117MRA_2118NC_009525
308Mycobacterium tuberculosis H37Ra4119 MRA_2520MRA_2519NC_009525
309Mycobacterium tuberculosis H37Ra4120 MRA_2554MRA_2553NC_009525
310Mycobacterium tuberculosis H37Ra4121 MRA_2557MRA_2558NC_009525
311Mycobacterium tuberculosis H37Ra4122 MRA_2574MRA_2573NC_009525
312Mycobacterium tuberculosis H37Ra4123 MRA_2576MRA_2575NC_009525
313Mycobacterium tuberculosis H37Ra4124 MRA_2578MRA_2579NC_009525
314Mycobacterium tuberculosis H37Ra4126 MRA_2630MRA_2629ANC_009525
315Mycobacterium tuberculosis H37Ra4127 MRA_2782MRA_2783NC_009525
316Mycobacterium tuberculosis H37Ra4128 MRA_2784MRA_2785NC_009525
317Mycobacterium tuberculosis H37Ra4130 MRA_2896MRA_2895ANC_009525
318Mycobacterium tuberculosis H37Ra4134 MRA_3362MRA_3363NC_009525
319Mycobacterium tuberculosis H37Ra4138 MRA_3732MRA_3733NC_009525
320Mycobacterium tuberculosis H37Rv76 Rv0582Rv0581NC_000962
321Mycobacterium tuberculosis H37Rv125 experimental Rv2872Rv2871NC_000962
322Mycobacterium tuberculosis H37Rv129 experimental Rv3320cRv3321cNC_000962
323Mycobacterium tuberculosis H37Rv99 Rv1741Rv1740NC_000962
324Mycobacterium tuberculosis H37Rv98 Rv1720cRv1721cNC_000962
325Mycobacterium tuberculosis H37Rv97 experimental Rv1561Rv1560NC_000962
326Mycobacterium tuberculosis H37Rv94 experimental Rv1397cRv1398cNC_000962
327Mycobacterium tuberculosis H37Rv92 Rv1242Rv1241NC_000962
328Mycobacterium tuberculosis H37Rv91 Rv1114Rv1113NC_000962
329Mycobacterium tuberculosis H37Rv87 experimental Rv0749Rv0748NC_000962
330Mycobacterium tuberculosis H37Rv85 experimental Rv0661cRv0662cNC_000962
331Mycobacterium tuberculosis H37Rv83 experimental Rv0656cRv0657cNC_000962
332Mycobacterium tuberculosis H37Rv81 Rv0624Rv0623NC_000962
333Mycobacterium tuberculosis H37Rv6246 experimental Rv1982cRv1982aNC_000962
334Mycobacterium tuberculosis H37Rv6241 experimental Rv0065Rv0064ANC_000962
335Mycobacterium tuberculosis H37Rv72 Rv0240Rv0239NC_000962
336Mycobacterium tuberculosis H37Rv74 experimental Rv0301Rv0300NC_000962
337Mycobacterium tuberculosis H37Rv75 Rv0549cRv0550cNC_000962
338Mycobacterium tuberculosis H37Rv79 experimental Rv0609Rv0608NC_000962
339Mycobacterium tuberculosis H37Rv112 experimental Rv2494Rv2493NC_000962
340Mycobacterium tuberculosis H37Rv111 experimental Rv2103cRv2104cNC_000962
341Mycobacterium tuberculosis H37Rv107 experimental Rv2010Rv2009NC_000962
342Mycobacterium tuberculosis H37Rv102 Rv1953Rv1952NC_000962
343Mycobacterium tuberculosis H37Rv100 Rv1838cRv1839cNC_000962
344Mycobacterium tuberculosis H37Rv113 Rv2527Rv2526NC_000962
345Mycobacterium tuberculosis H37Rv114 Rv2530cRv2530ANC_000962
346Mycobacterium tuberculosis H37Rv115 Rv2546Rv2545NC_000962
347Mycobacterium tuberculosis H37Rv116 Rv2548Rv2547NC_000962
348Mycobacterium tuberculosis H37Rv117 experimental Rv2549cRv2550cNC_000962
349Mycobacterium tuberculosis H37Rv119 Rv2602Rv2601ANC_000962
350Mycobacterium tuberculosis H37Rv121 Rv2757cRv2758cNC_000962
351Mycobacterium tuberculosis H37Rv122 Rv2759cRv2760cNC_000962
352Mycobacterium vanbaalenii PYR-13282 Mvan_1171Mvan_1170NC_008726
353Mycobacterium vanbaalenii PYR-13283 Mvan_1710Mvan_1709NC_008726
354Natronomonas pharaonis DSM 21602013 NP4666ANP4664ANC_007426
355Natronomonas pharaonis DSM 21602015 NP6012ANP6014ANC_007427
356Natronomonas pharaonis DSM 21602012 NP3836ANP3834ANC_007426
357Natronomonas pharaonis DSM 21602014 NP4840ANP4838ANC_007426
358Neisseria gonorrhoeae FA 10901755 NGO0907NGO0908NC_002946
359Neisseria gonorrhoeae NCCP119455816 NGK_0895NGK_0894NC_011035
360Nitrobacter hamburgensis X142632 Nham_4575Nham_4574NC_007961
361Nitrobacter hamburgensis X142633 Nham_4577Nham_4578NC_007961
362Nitrosococcus oceani ATCC 197072047 Noc_1522Noc_1521NC_007484
363Nitrosococcus oceani ATCC 197072033 Noc_0413Noc_0414NC_007484
364Nitrosococcus oceani ATCC 197072046 Noc_1461Noc_1462NC_007484
365Nitrosomonas europaea ATCC 19718904 NE1064NE1065NC_004757
366Nitrosomonas europaea ATCC 19718931 NE1589NE1590NC_004757
367Nitrosomonas europaea ATCC 19718928 NE1581NE1582NC_004757
368Nitrosomonas eutropha C912899 Neut_1359Neut_1360NC_008344
369Nocardia farcinica IFM 101521087 nfa23730nfa23740NC_006361
370Nostoc punctiforme PCC 73102 (Nostoc punctiforme ATCC 29133)5473 Npun_F6456Npun_F6455NC_010628
371Nostoc punctiforme PCC 73102 (Nostoc punctiforme ATCC 29133)5463 Npun_F4285Npun_F4284NC_010628
372Nostoc sp. PCC 7120 (Anabaena sp. PCC 7120)493 alr4601asr4600NC_003272
373Nostoc sp. PCC 7120 (Anabaena sp. PCC 7120)479 asl3128asl3129NC_003272
374Nostoc sp. PCC 7120 (Anabaena sp. PCC 7120)470 all2196asl2197NC_003272
375Novosphingobium aromaticivorans DSM 124442422 Saro_1201Saro_1200NC_007794
376Ochrobactrum anthropi ATCC 491884333 Oant_4604Oant_4603NC_009669
377Ochrobactrum anthropi ATCC 491884337 Oant_4717Oant_4718NC_009671
378Ochrobactrum anthropi ATCC 491884326 Oant_0618Oant_0619NC_009667
379Ochrobactrum anthropi ATCC 491884328 Oant_0633Oant_0632NC_009667
380Paracoccus denitrificans PD12223212 Pden_2075Pden_2074NC_008686
381Paracoccus denitrificans PD12223204 Pden_0103Pden_0104NC_008686
382Parvibaculum lavamentivorans DS-14403 Plav_1214Plav_1215NC_009719
383Parvibaculum lavamentivorans DS-14418 Plav_3521Plav_3520NC_009719
384Pelodictyon phaeoclathratiforme BU-15863 Ppha_1720Ppha_1718NC_011060
385Pelotomaculum thermopropionicum SI3881 PTH_2792PTH_2791NC_009454
386Pelotomaculum thermopropionicum SI3873 PTH_2303PTH_2304NC_009454
387Pelotomaculum thermopropionicum SI3879 PTH_2698PTH_2699NC_009454
388Pelotomaculum thermopropionicum SI3880 PTH_2783PTH_2784NC_009454
389Pelotomaculum thermopropionicum SI3883 PTH_2807PTH_2808NC_009454
390Photorhabdus luminescens subsp. laumondii TTO11233 plu3057plu3058NC_005126
391Photorhabdus luminescens subsp. laumondii TTO11224 plu2368plu2369NC_005126
392Polaromonas naphthalenivorans CJ23319 Pnap_4764Pnap_4765NC_008761
393Polaromonas naphthalenivorans CJ23320 Pnap_4802Pnap_4803NC_008761
394Polaromonas sp. JS6662587 Bpro_4019Bpro_4020NC_007948
395Polaromonas sp. JS6662588 Bpro_4104Bpro_4105NC_007948
396Propionibacterium acnes KPA1712021254 PPA2073PPA2075NC_006085
397Pseudomonas mendocina ymp3811 Pmen_1045Pmen_1046NC_009439
398Pseudomonas syringae pv. phaseolicola 1448A1936 PSPPH_A0034PSPPH_A0035NC_007274
399Pseudomonas syringae pv. phaseolicola 1448A1940 PSPPH_A0136PSPPH_A0137NC_007274
400Pseudomonas syringae pv. tomato str. DC30001796 PSPTO_B0073PSPTO_B0074NC_004632
401Pseudomonas syringae pv. tomato str. DC30001794 PSPTO_B0018PSPTO_B0019NC_004632
402Pyrobaculum aerophilum str. IM2535 experimental PAE2754PAE2755NC_003364
403Pyrobaculum aerophilum str. IM2516 experimental PAE0151PAE0152NC_003364
404Pyrobaculum aerophilum str. IM2519 PAE0337PAE0335NC_003364
405Pyrobaculum arsenaticum DSM 135143714 Pars_1065Pars_1066NC_009376
406Pyrobaculum arsenaticum DSM 135143713 Pars_1049Pars_1050NC_009376
407Pyrobaculum arsenaticum DSM 135143710 Pars_1017Pars_1018NC_009376
408Pyrobaculum arsenaticum DSM 135143702 Pars_0424Pars_0425NC_009376
409Pyrobaculum arsenaticum DSM 135143719 Pars_1262Pars_1261NC_009376
410Pyrobaculum islandicum DSM 41843251 Pisl_1536Pisl_1537NC_008701
411Pyrobaculum neutrophilum V24Sta5285 Tneu_0230Tneu_0231NC_010525
412Pyrococcus abyssi GE5985 PAB1755PAB1754NC_000868
413Pyrococcus abyssi GE5980 PAB2325PAB2324NC_000868
414Pyrococcus abyssi GE5982 PAB2079PAB3103NC_000868
415Pyrococcus furiosus DSM 3638552 PF1223PF1222NC_003413
416Pyrococcus furiosus DSM 3638542 PF0355PF0355.1nNC_003413
417Pyrococcus furiosus DSM 3638555 PF1352PF1353NC_003413
418Pyrococcus furiosus DSM 3638545 PF0773PF0774NC_003413
419Pyrococcus furiosus DSM 3638546 PF0776PF0775NC_003413
420Pyrococcus furiosus DSM 3638551 PF1206PF1207NC_003413
421Pyrococcus horikoshii OT3855 PH0469PH0468NC_000961
422Pyrococcus horikoshii OT3850 PH0098PH0097.2nNC_000961
423Pyrococcus horikoshii OT3851 PH0389PH0389.1nNC_000961
424Pyrococcus horikoshii OT3861 PHS031aPHS031NC_000961
425Pyrococcus horikoshii OT3859 PH0708PH0707.2nNC_000961
426Pyrococcus horikoshii OT3856 PH0500PH0500.1nNC_000961
427Rhizobium etli CFN 422365 RHE_PE00296RHE_PE00297NC_007765
428Rhizobium etli CIAT 6525736 RHECIAT_CH0000456RHECIAT_CH0000455NC_010994
429Rhizobium leguminosarum bv. viciae 38412958 pRL120076pRL120075NC_008378
430Rhizobium leguminosarum bv. viciae 38412961 pRL120133pRL120134NC_008378
431Rhodopseudomonas palustris BisA532989 RPE_2384RPE_2383NC_008435
432Rhodopseudomonas palustris BisA533006 RPE_4859RPE_4860NC_008435
433Rhodopseudomonas palustris BisA532991 RPE_2552RPE_2551NC_008435
434Rhodopseudomonas palustris BisA532999 RPE_4065RPE_4064NC_008435
435Rhodopseudomonas palustris BisB182531 RPC_3944RPC_3943NC_007925
436Rhodopseudomonas palustris BisB182502 RPC_0722RPC_0723NC_007925
437Rhodopseudomonas palustris BisB182503 RPC_0805RPC_0804NC_007925
438Rhodopseudomonas palustris BisB182507 RPC_1344RPC_1343NC_007925
439Rhodopseudomonas palustris BisB182519 RPC_2268RPC_2267NC_007925
440Rhodopseudomonas palustris BisB182521 RPC_2435RPC_2434NC_007925
441Rhodopseudomonas palustris BisB182542 RPC_4800RPC_4801NC_007925
442Rhodopseudomonas palustris BisB182535 RPC_4151RPC_4150NC_007925
443Rhodopseudomonas palustris BisB52622 RPD_3138RPD_3137NC_007958
444Rhodopseudomonas palustris BisB52614 RPD_1445RPD_1446NC_007958
445Rhodopseudomonas palustris BisB52611 RPD_0538RPD_0537NC_007958
446Rhodopseudomonas palustris CGA0091492 RPA4142RPA4141NC_005296
447Rhodopseudomonas palustris HaA22405 RPB_1592RPB_1593NC_007778
448Rhodopseudomonas palustris HaA22409 RPB_2332RPB_2333NC_007778
449Rhodopseudomonas palustris HaA22408 RPB_2119RPB_2118NC_007778
450Rhodopseudomonas palustris TIE-15794 Rpal_3938Rpal_3939NC_011004
451Rhodopseudomonas palustris TIE-15800 Rpal_4620Rpal_4619NC_011004
452Rhodospirillum rubrum ATCC 111702248 Rru_A1415Rru_A1416NC_007643
453Rhodospirillum rubrum ATCC 111702245 Rru_A1062Rru_A1061NC_007643
454Roseiflexus castenholzii DSM 139414444 Rcas_1166Rcas_1167NC_009767
455Roseiflexus sp. RS-14059 RoseRS_1884RoseRS_1883NC_009523
456Saccharopolyspora erythraea NRRL 23383628 SACE_5826SACE_5827NC_009142
457Salinibacter ruber DSM 138552312 SRU_0198SRU_0197NC_007677
458Salinibacter ruber DSM 138552320 SRU_1578SRU_1579NC_007677
459Salinibacter ruber DSM 138552314 SRU_0210SRU_0209NC_007677
460Salinibacter ruber DSM 138552313 SRU_0207SRU_0206NC_007677
461Salmonella enterica subsp. enterica serovar Paratyphi A str.5956 SSPA3604SSPA3603NC_011147
462Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC1659 SPA3875SPA3874NC_006511
463Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB74809 SPAB_04995SPAB_04994NC_010102
464Salmonella enterica subsp. enterica serovar Typhi str. CT18827 STY3844STY3845NC_003198
465Salmonella enterica subsp. enterica serovar Typhi str. Ty2753 t3587t3588NC_004631
466Serratia proteamaculans 5684539 Spro_4619Spro_4618NC_009832
467Serratia proteamaculans 5684519 Spro_0051Spro_0052NC_009832
468Sinorhizobium meliloti 1021870 SMc01932SMc01933NC_003047
469Sinorhizobium meliloti 1021867 SMc00900SMc00899NC_003047
470Sinorhizobium meliloti 1021876 SMc02715SMc02716NC_003047
471Sinorhizobium meliloti 1021882 SMc02987SMc02988NC_003047
472Sphingomonas wittichii RW14027 Swit_3889Swit_3888NC_009511
473Sphingomonas wittichii RW14023 Swit_2631Swit_2632NC_009511
474Sphingopyxis alaskensis RB22562719 Sala_0697Sala_0696NC_008048
475Staphylothermus marinus F13528 Smar_0674Smar_0673NC_009033
476Staphylothermus marinus F13533 Smar_1565Smar_1566NC_009033
477Staphylothermus marinus F13530 Smar_1528Smar_1527NC_009033
478Streptomyces avermitilis MA-4680 = NBRC 14893430 SAV_5694SAV_5693NC_003155
479Sulfolobus acidocaldarius DSM 6391922 Saci_1790Saci_1791NC_007181
480Sulfolobus acidocaldarius DSM 6391924 Saci_1883Saci_1882NC_007181
481Sulfolobus acidocaldarius DSM 6391930 Saci_2080Saci_2079NC_007181
482Sulfolobus acidocaldarius DSM 6391929 Saci_2002Saci_2003NC_007181
483Sulfolobus acidocaldarius DSM 6391927 Saci_1981Saci_1980NC_007181
484Sulfolobus acidocaldarius DSM 6391921 Saci_0467Saci_0468NC_007181
485Sulfolobus acidocaldarius DSM 6391923 Saci_1813Saci_1812NC_007181
486Sulfolobus solfataricus P2945 SSO1493SSO1494NC_002754
487Sulfolobus tokodaii str. 7386 ST1125STS128NC_003106
488Sulfolobus tokodaii str. 7400 ST2012STS214NC_003106
489Sulfolobus tokodaii str. 7399 ST1943STS208NC_003106
490Sulfolobus tokodaii str. 7393 ST1639ST1640NC_003106
491Sulfolobus tokodaii str. 7392 ST1628STS188NC_003106
492Sulfolobus tokodaii str. 7388 STS143STS144NC_003106
493Sulfolobus tokodaii str. 7381 ST0897STS101NC_003106
494Sulfolobus tokodaii str. 7372 STS083STS084NC_003106
495Synechococcus elongatus PCC 6301 (Synechococcus leopoliensis SAG)1627 syc0004_dsyc0003_dNC_006576
496Synechococcus elongatus PCC 6301 (Synechococcus leopoliensis SAG)1632 syc0981_csyc0980_cNC_006576
497Synechococcus elongatus PCC 79422191 Synpcc7942_0540Synpcc7942_0541NC_007604
498Synechococcus elongatus PCC 79422195 Synpcc7942_1545Synpcc7942_1544NC_007604
499Synechococcus elongatus PCC 79422196 Synpcc7942_2147Synpcc7942_2146NC_007604
500Synechococcus sp. CC93112872 sync_0135sync_0136NC_008319
501Synechococcus sp. WH 81021263 SYNW0071SYNW0072NC_005070
502Synechococcus sp. WH 81021264 SYNW0214SYNW0215NC_005070
503Synechococcus sp. WH 81021271 SYNW0573SYNW0572NC_005070
504Synechocystis sp. PCC 68036113 MYO_440MYO_450NC_020287
505Synechocystis sp. PCC 6803 (Synechocystis PCC6803)1817 sll8011sll8012NC_005231
506Synechocystis sp. PCC 6803 (Synechocystis PCC6803)1810 sll7003ssl7004NC_005230
507Synechocystis sp. PCC 6803 (Synechocystis PCC6803)1809 slr5116ssr5117NC_005229
508Synechocystis sp. PCC 6803 (Synechocystis PCC6803)1811 ssl7007sll7006NC_005230
509Syntrophobacter fumaroxidans MPOB3113 Sfum_0894Sfum_0895NC_008554
510Syntrophomonas wolfei subsp. wolfei str. Goettingen G3112931 Swol_1570Swol_1571NC_008346
511Thermoanaerobacter tengcongensis MB4 (Caldanaerobacter subterraneus)773 TTE2584TTE2583NC_003869
512Thermococcus kodakarensis KOD11567 TK0374TK0373NC_006624
513Thermococcus kodakarensis KOD11578 TK0972TK0973NC_006624
514Thermococcus kodakarensis KOD11594 TK1751TK1752NC_006624
515Thermococcus kodakarensis KOD11595 TK1763TK1762NC_006624
516Thermococcus kodakarensis KOD11570 TK0696TK0695NC_006624
517Thermofilum pendens Hrk 53223 Tpen_1390Tpen_1389NC_008698
518Thermofilum pendens Hrk 53213 Tpen_0050Tpen_0049NC_008698
519Thermofilum pendens Hrk 53218 Tpen_1187Tpen_1188NC_008698
520Thermofilum pendens Hrk 53222 Tpen_1378Tpen_1379NC_008698
521Thermofilum pendens Hrk 53226 Tpen_1436Tpen_1435NC_008698
522Thermofilum pendens Hrk 53230 Tpen_1673Tpen_1674NC_008698
523Thermofilum pendens Hrk 53235 Tpen_1694Tpen_1695NC_008698
524Thermus thermophilus HB271606 TTC0125TTC0126NC_005835
525Thermus thermophilus HB81850 TTHB233TTHB234NC_006462
526Thermus thermophilus HB81367 TTHA0501TTHA0502NC_006461
527Thermus thermophilus HB81373 TTHA1052TTHA1051NC_006461
528Thermus thermophilus HB81847 TTHB135TTHB136NC_006462
529Treponema denticola ATCC 354051682 TDE0197TDE0196NC_002967
530Treponema denticola ATCC 354051710 TDE2127TDE2126NC_002967
531Treponema denticola ATCC 354051714 TDE2532TDE2531NC_002967
532Treponema denticola ATCC 354051716 TDE2577TDE2578NC_002967
533Treponema denticola ATCC 354051707 TDE1961TDE1962NC_002967
534Treponema denticola ATCC 354051697 TDE0887TDE0888NC_002967
535Treponema denticola ATCC 354051685 TDE0280TDE0281NC_002967
536Verminephrobacter eiseniae EF01-23426 Veis_0177Veis_0176NC_008786
537Verminephrobacter eiseniae EF01-23450 Veis_3767Veis_3768NC_008786
538Verminephrobacter eiseniae EF01-23448 Veis_3474Veis_3473NC_008786
539Xanthobacter autotrophicus Py24426 Xaut_2191Xaut_2192NC_009720
540Xanthobacter autotrophicus Py24388 Xaut_4797Xaut_4798NC_009717
541Xanthobacter autotrophicus Py24387 Xaut_4793Xaut_4794NC_009717
542Xanthobacter autotrophicus Py24430 Xaut_3923Xaut_3924NC_009720
543Xanthomonas axonopodis pv. citri str. 306742 XAC4315XAC4314NC_003919
544Xylella fastidiosa M125256 Xfasm12_2302Xfasm12_2303NC_010513

experimental Data derived from experimental literature


Antitoxin domain: RHH. RHH_2: Uncharacterized protein family (UPF0156). This family of proteins are about 80 amino acids in length and their function is unknown. The proteins contain a conserved GRY motif. This family appears to be related to ribbon-helix-helix DNA-binding proteins

Toxin domain: PIN. This PIN (PilT N terminus) domain is a compact domain of about 100 amino acids. The domain has two nearly invariant aspartates. The function of the PIN domain is unknown but a role in signaling appears likely given the presence of this domain is StbB and DIS3. The majority of PIN-domain proteins found in prokaryotes are the toxic components of toxin-antitoxin operon, and toxin-antitoxin gene cassettes, though first found in plasmids, are found to be abundant in free-living prokaryotes, including many pathogenic bacteria. These loci provide a control mechanism that helps free-living prokaryotes cope with nutritional stress. In many genomes PIN domains are annotated as VapC and are part of the VapBC toxin-antitoxin operons. These operons are expanded in number in several unrelated micro-organisisms including Mycobacterium tuberculosis and Sulfolobus solfataricus.


Structure
Crystal structure of (YP_321193.1) from Anabaena variabilis ATCC 29413 at 2.00 A resolution [PDB ID: 2GA1]
(1) Robson J et al. (2009) The vapBC operon from Mycobacterium smegmatis is an autoregulatedtoxin-antitoxin module that controls growth via inhibition of translation. J Mol Biol 390(3):353-67. [PudMed:19445953] experimental
(2) McKenzie JL; Robson J; Berney M; Smith TC; Ruthe A; Gardner PP; Arcus VL; Cook GM (2012) A VapBC toxin-antitoxin module is a posttranscriptional regulator of metabolic flux in mycobacteria J Bacteriol 194(9):2189-204. [PudMed:22366418] experimental
(3) Ramage HR et al. (2009) Comprehensive functional analysis of Mycobacterium tuberculosis toxin-antitoxinsystems: implications for pathogenesis, stress responses, and evolution. PLoS Genet 5(12):e1000767. [PudMed:20011113] experimental
(4) Gupta A. (2009) Killing activity and rescue function of genome-wide toxin-antitoxin loci of Mycobacterium tuberculosis. FEMS Microbiol Lett. 290(1):45-53.. [PudMed:19016878] experimental
(5) Makarova KS et al. (2009) Comprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes. Biol Direct 4:19. [PudMed:19493340] in_silico
(6) Das U; Kumar N; Gourinath S; Srinivasan A (2013) Preliminary crystallographic analysis of recombinant VapBC-15 toxin-antitoxin complex from Mycobacterium tuberculosis Acta Crystallogr Sect F Struct Biol Cryst Commun 69(Pt 11):1242-5. [PudMed:24192359] 3D_structure
(7) Min AB; Miallau L; Sawaya MR; Habel J; Cascio D; Eisenberg D (2012) The crystal structure of the Rv0301-Rv0300 VapBC-3 toxin-antitoxin complex from M. tuberculosis reveals a Mg(2)(+) ion in the active site and a putative RNA-binding site Protein Sci 21(11):1754-67. [PudMed:23011806] 3D_structure
(8) Winther KS; Brodersen DE; Brown AK; Gerdes K (2013) VapC20 of Mycobacterium tuberculosis cleaves the sarcin-ricin loop of 23S rRNA Nat Commun 4:2796. [PudMed:24225902] experimental
(9) McKenzie JL; Duyvestyn JM; Smith T; Bendak K; Mackay J; Cursons R; Cook GM; Arcus VL (2012) Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry RNA 18(6):1267-78. [PudMed:22539524] experimental