TADB
TA Pair: PHD-PIN
#OrganismToxinAntitoxinLocus IDReplicon
1Acaryochloris marina MBIC110174646 AM1_E0087AM1_E0088NC_009930
2Acaryochloris marina MBIC110174632 AM1_3812AM1_3813NC_009925
3Acaryochloris marina MBIC110174643 AM1_A0134AM1_A0133NC_009926
4Acidithiobacillus ferrooxidans ATCC 539936014 Lferr_2867Lferr_2866NC_011206
5Acidithiobacillus ferrooxidans ATCC 539936013 Lferr_2769Lferr_2770NC_011206
6Acidithiobacillus ferrooxidans ATCC 539935995 Lferr_0576Lferr_0577NC_011206
7Acidithiobacillus ferrooxidans ATCC 539936012 Lferr_2597Lferr_2596NC_011206
8Acidithiobacillus ferrooxidans ATCC 539935989 Lferr_0088Lferr_0087NC_011206
9Acidovorax citrulli AAC00-13311 Aave_3368Aave_3369NC_008752
10Actinobacillus pleuropneumoniae serovar 3 str. JL034917 APJL_1219APJL_1220NC_010278
11Actinobacillus pleuropneumoniae serovar 3 str. JL034923 APJL_1864APJL_1865NC_010278
12Actinobacillus pleuropneumoniae serovar 5b str. L203570 APL_1828APL_1829NC_009053
13Actinobacillus pleuropneumoniae serovar 5b str. L203564 APL_1206APL_1207NC_009053
14Actinobacillus pleuropneumoniae serovar 7 str. AP765724 APP7_1914APP7_1915NC_010939
15Actinobacillus pleuropneumoniae serovar 7 str. AP765720 APP7_1257APP7_1258NC_010939
16Albidiferax ferrireducens T118 (Rhodoferax ferrireducens T118)2483 Rfer_0624Rfer_0623NC_007908
17Azoarcus sp. BH723253 azo0287azo0288NC_008702
18Azorhizobium caulinodans ORS 5714653 AZC_3672AZC_3673NC_009937
19Beijerinckia indica subsp. indica ATCC 90395401 Bind_3774Bind_3775NC_010580
20Beijerinckia indica subsp. indica ATCC 90395412 Bind_3526Bind_3527NC_010581
21Beijerinckia indica subsp. indica ATCC 90395409 Bind_2539Bind_2538NC_010581
22Bradyrhizobium diazoefficiens USDA 110843 experimental bll2434bsl2435NC_004463
23Bradyrhizobium sp. ORS 2783853 BRADO7084BRADO7083NC_009445
24Burkholderia ambifaria AMMD2969 Bamb_0628Bamb_0629NC_008390
25Burkholderia cenocepacia AU 10542735 Bcen_2333Bcen_2334NC_008060
26Burkholderia cenocepacia AU 10542729 Bcen_0025Bcen_0024NC_008060
27Burkholderia cenocepacia HI24243107 Bcen2424_2947Bcen2424_2948NC_008542
28Burkholderia cenocepacia HI24243101 Bcen2424_0045Bcen2424_0046NC_008542
29Burkholderia cenocepacia MC0-35229 Bcenmc03_0064Bcenmc03_0065NC_010508
30Burkholderia cenocepacia MC0-35236 Bcenmc03_2968Bcenmc03_2969NC_010508
31Burkholderia cenocepacia MC0-35231 Bcenmc03_0706Bcenmc03_0707NC_010508
32Burkholderia lata2099 Bcep18194_A6299Bcep18194_A6300NC_007510
33Burkholderia lata2093 Bcep18194_A3824Bcep18194_A3825NC_007510
34Burkholderia multivorans ATCC 176164800 Bmul_2648Bmul_2647NC_010084
35Burkholderia phytofirmans PsJN5502 Bphyt_4379Bphyt_4380NC_010676
36Caldicellulosiruptor saccharolyticus DSM 89033783 Csac_0209Csac_0208NC_009437
37Caldicellulosiruptor saccharolyticus DSM 89033796 Csac_2256Csac_2257NC_009437
38Candidatus Desulforudis audaxviator MP104C5125 Daud_0206Daud_0205NC_010424
39Candidatus Desulforudis audaxviator MP104C5145 Daud_2130Daud_2131NC_010424
40Candidatus Desulforudis audaxviator MP104C5126 Daud_0319Daud_0320NC_010424
41Candidatus Desulforudis audaxviator MP104C5123 Daud_0061Daud_0062NC_010424
42Candidatus Koribacter versatilis Ellin3452655 Acid345_0993Acid345_0994NC_008009
43Candidatus Koribacter versatilis Ellin3452662 Acid345_2636Acid345_2637NC_008009
44Candidatus Koribacter versatilis Ellin3452670 Acid345_4435Acid345_4434NC_008009
45Candidatus Koribacter versatilis Ellin3452658 Acid345_1397Acid345_1398NC_008009
46Candidatus Solibacter usitatus Ellin60763057 Acid_0896Acid_0897NC_008536
47Candidatus Solibacter usitatus Ellin60763062 Acid_1772Acid_1771NC_008536
48Candidatus Solibacter usitatus Ellin60763071 Acid_2407Acid_2406NC_008536
49Candidatus Solibacter usitatus Ellin60763073 Acid_2753Acid_2752NC_008536
50Carboxydothermus hydrogenoformans Z-29012089 CHY_2539CHY_2540NC_007503
51Carboxydothermus hydrogenoformans Z-29012083 CHY_1722CHY_1721NC_007503
52Chelativorans sp. BNC12798 Meso_4581Meso_4580NC_008244
53Chelativorans sp. BNC12796 Meso_4552Meso_4551NC_008243
54Chlorobium phaeobacteroides BS15692 Cphamn1_2339Cphamn1_2340NC_010831
55Chlorobium phaeobacteroides BS15689 Cphamn1_2220Cphamn1_2221NC_010831
56Chloroflexus aurantiacus J-10-fl4888 Caur_2465Caur_2466NC_010175
57Coxiella burnetii RSA 3314819 COXBURSA331_A1443COXBURSA331_A1444NC_010117
58Coxiella burnetii RSA 493319 CBU_1294CBU_1295NC_002971
59Cupriavidus taiwanensis LMG 194245303 pRALTA_0622pRALTA_0623NC_010529
60Cyanothece sp. ATCC 511425315 cce_0583cce_0582NC_010546
61Cyanothece sp. ATCC 511425311 cce_0024cce_0023NC_010546
62Cyanothece sp. ATCC 511425339 cce_3116cce_3115NC_010546
63Cyanothece sp. ATCC 511425335 cce_2869cce_2870NC_010546
64Cyanothece sp. ATCC 511425319 cce_1228cce_1227NC_010546
65Dechloromonas aromatica RCB1956 Daro_2534Daro_2535NC_007298
66Deinococcus geothermalis DSM 113002677 Dgeo_2733Dgeo_2734NC_008010
67Delftia acidovorans SPH-14765 Daci_3962Daci_3961NC_010002
68Delftia acidovorans SPH-14763 Daci_3012Daci_3011NC_010002
69Delftia acidovorans SPH-14757 Daci_1390Daci_1389NC_010002
70Desulfococcus oleovorans Hxd34672 Dole_1783Dole_1782NC_009943
71Desulfococcus oleovorans Hxd34667 Dole_0924Dole_0923NC_009943
72Desulfococcus oleovorans Hxd34677 Dole_1902Dole_1901NC_009943
73Desulfococcus oleovorans Hxd34676 Dole_1845Dole_1844NC_009943
74Desulfococcus oleovorans Hxd34671 Dole_1760Dole_1759NC_009943
75Frankia alni ACN14a2848 FRAAL0552FRAAL0553NC_008278
76Frankia alni ACN14a2849 FRAAL0563FRAAL0564NC_008278
77Frankia sp. CcI32398 Francci3_4336Francci3_4337NC_007777
78Frankia sp. CcI32397 Francci3_4109Francci3_4108NC_007777
79Frankia sp. CcI32368 Francci3_0141Francci3_0142NC_007777
80Frankia sp. EAN1pec4603 Franean1_0552Franean1_0553NC_009921
81Geobacter lovleyi SZ5628 Glov_1581Glov_1580NC_010814
82Geobacter lovleyi SZ5642 Glov_3572Glov_3573NC_010814
83Geobacter metallireducens GS-152173 Gmet_3076Gmet_3077NC_007517
84Geobacter uraniireducens Rf43937 Gura_0713Gura_0714NC_009483
85Geobacter uraniireducens Rf43944 Gura_1139Gura_1140NC_009483
86Geobacter uraniireducens Rf43973 Gura_2398Gura_2397NC_009483
87Geobacter uraniireducens Rf43921 Gura_0038Gura_0037NC_009483
88Geobacter uraniireducens Rf43935 Gura_0629Gura_0630NC_009483
89Geobacter uraniireducens Rf43991 Gura_3865Gura_3866NC_009483
90Geobacter uraniireducens Rf43974 Gura_2455Gura_2456NC_009483
91Gloeobacter violaceus PCC 74211464 gll3798gsl3799NC_005125
92Gloeobacter violaceus PCC 74211412 glr0279gsr0278NC_005125
93Gloeobacter violaceus PCC 74211416 gll0632gsl0633NC_005125
94Gloeobacter violaceus PCC 74211431 gll1679gsl1680NC_005125
95Gloeobacter violaceus PCC 74211438 gll2024gsl2025NC_005125
96Gloeobacter violaceus PCC 74211444 glr2382gsr2381NC_005125
97Gloeobacter violaceus PCC 74211455 gll2982gsl2983NC_005125
98Gloeobacter violaceus PCC 74211463 gll3555gsl3556NC_005125
99Gluconobacter oxydans 621H1856 GOX2554GOX2553NC_006672
100Gluconobacter oxydans 621H1351 GOX1501GOX1500NC_006677
101Halorhodospira halophila SL13470 Hhal_0789Hhal_0788NC_008789
102Jannaschia sp. CCS12467 Jann_1434Jann_1433NC_007802
103Kineococcus radiotolerans SRS30216 = ATCC BAA-1494310 Krad_0354Krad_0355NC_009664
104Kineococcus radiotolerans SRS30216 = ATCC BAA-1494313 Krad_2150Krad_2149NC_009664
105Kineococcus radiotolerans SRS30216 = ATCC BAA-1494315 Krad_4396Krad_4395NC_009664
106Leptospira biflexa serovar Patoc strain Patoc 1 (Ames)5695 LBF_0418LBF_0417NC_010842
107Leptospira biflexa serovar Patoc strain Patoc 1 (Paris)5715 LEPBI_p0050LEPBI_p0049NC_010844
108Leptospira borgpetersenii serovar Hardjo-bovis str. JB1973024 LBJ_0764LBJ_0763NC_008510
109Leptospira borgpetersenii serovar Hardjo-bovis str. L5503019 LBL_2314LBL_2315NC_008508
110Leptospira interrogans serovar Copenhageni str. Fiocruz L1-1301519 LIC12713LIC12712NC_005823
111Leptospira interrogans serovar Lai str. 56601654 LA_1799LA_1798NC_004342
112Leptothrix cholodnii SP-65274 Lcho_1565Lcho_1566NC_010524
113Magnetospirillum magneticum AMB-12232 amb1706amb1707NC_007626
114Maricaulis maris MCS102946 Mmar10_1544Mmar10_1545NC_008347
115Methanospirillum hungatei JF-12434 Mhun_0506Mhun_0505NC_007796
116Methylibium petroleiphilum PM13510 Mpe_A3783Mpe_A3784NC_008825
117Methylobacterium extorquens PA14877 Mext_2930Mext_2929NC_010172
118Methylobacterium populi BJ0015566 Mpop_3315Mpop_3314NC_010725
119Methylobacterium populi BJ0015562 Mpop_3051Mpop_3050NC_010725
120Methylobacterium populi BJ0015563 Mpop_3163Mpop_3164NC_010725
121Methylobacterium populi BJ0015576 Mpop_4539Mpop_4538NC_010725
122Methylobacterium sp. 4-465240 M446_1967M446_1968NC_010511
123Microcystis aeruginosa NIES-8434990 MAE_33180MAE_33190NC_010296
124Microcystis aeruginosa NIES-8434975 MAE_23820MAE_23810NC_010296
125Microcystis aeruginosa NIES-8434939 MAE_06990MAE_07000NC_010296
126Microcystis aeruginosa NIES-8435030 MAE_58010MAE_58020NC_010296
127Microcystis aeruginosa NIES-8435028 MAE_56140MAE_56150NC_010296
128Moorella thermoacetica ATCC 390732295 Moth_2207Moth_2206NC_007644
129Moorella thermoacetica ATCC 390732297 Moth_2333Moth_2334NC_007644
130Moorella thermoacetica ATCC 390732285 Moth_0885Moth_0884NC_007644
131Moorella thermoacetica ATCC 390732280 Moth_0652Moth_0653NC_007644
132Moorella thermoacetica ATCC 390732293 Moth_2092Moth_2091NC_007644
133Mycobacterium avium subsp. paratuberculosis K-101327 MAP2027cMAP2028cNC_002944
134Mycobacterium bovis AF2122/971175 Mb3416cMb3417cNC_002945
135Mycobacterium bovis AF2122/971167 Mb2853cMb2854cNC_002945
136Mycobacterium bovis AF2122/971130 Mb0643Mb0642NC_002945
137Mycobacterium bovis AF2122/971126 Mb0611cMb0612cNC_002945
138Mycobacterium bovis AF2122/971176 Mb3442Mb3441NC_002945
139Mycobacterium bovis AF2122/971170 Mb3206cMb3207cNC_002945
140Mycobacterium bovis BCG str. Pasteur 1173P23383 BCG_3478BCG_3477NC_008769
141Mycobacterium bovis BCG str. Pasteur 1173P23335 BCG_0641cBCG_0642cNC_008769
142Mycobacterium bovis BCG str. Pasteur 1173P23340 BCG_0673BCG_0672NC_008769
143Mycobacterium bovis BCG str. Pasteur 1173P23357 BCG_2001cBCG_2001ANC_008769
144Mycobacterium bovis BCG str. Pasteur 1173P23374 BCG_2849cBCG_2850cNC_008769
145Mycobacterium bovis BCG str. Pasteur 1173P23377 BCG_3206cBCG_3207cNC_008769
146Mycobacterium bovis BCG str. Pasteur 1173P23382 BCG_3453cBCG_3454cNC_008769
147Mycobacterium gilvum PYR-GCK3691 Mflv_5572Mflv_5571NC_009339
148Mycobacterium gilvum PYR-GCK3686 Mflv_3018Mflv_3019NC_009338
149Mycobacterium sp. KMS3264 Mkms_5933Mkms_5934NC_008704
150Mycobacterium sp. MCS2756 Mmcs_5531Mmcs_5532NC_008147
151Mycobacterium tuberculosis CDC1551285 MT3271MT3272NC_002755
152Mycobacterium tuberculosis CDC1551291 MT3516MT3515NC_002755
153Mycobacterium tuberculosis CDC1551290 MT3492MT3493NC_002755
154Mycobacterium tuberculosis CDC1551240 MT0625MT0626NC_002755
155Mycobacterium tuberculosis CDC1551248 MT0693MT0692.1NC_002755
156Mycobacterium tuberculosis CDC1551264 MT2012MT2013NC_002755
157Mycobacterium tuberculosis F114163 TBFG_11990TBFG_11991NC_009565
158Mycobacterium tuberculosis F114184 TBFG_13418TBFG_13419NC_009565
159Mycobacterium tuberculosis F114179 TBFG_13202TBFG_13203NC_009565
160Mycobacterium tuberculosis F114177 TBFG_12844TBFG_12845NC_009565
161Mycobacterium tuberculosis F114144 TBFG_10607TBFG_10608NC_009565
162Mycobacterium tuberculosis F114148 TBFG_10638TBFG_10637NC_009565
163Mycobacterium tuberculosis H37Ra4131 MRA_3214MRA_3215NC_009525
164Mycobacterium tuberculosis H37Ra4092 MRA_0636MRA_0635NC_009525
165Mycobacterium tuberculosis H37Ra4088 MRA_0603MRA_0604NC_009525
166Mycobacterium tuberculosis H37Ra4137 MRA_3448MRA_3447NC_009525
167Mycobacterium tuberculosis H37Ra4136 MRA_3424MRA_3425NC_009525
168Mycobacterium tuberculosis H37Ra4109 MRA_1971MRA_1972NC_009525
169Mycobacterium tuberculosis H37Rv123 Rv2829cRv2830cNC_000962
170Mycobacterium tuberculosis H37Rv82 experimental Rv0627Rv0626NC_000962
171Mycobacterium tuberculosis H37Rv6250 Rv2231ARv2231BNC_000962
172Mycobacterium tuberculosis H37Rv77 experimental Rv0595cRv0596cNC_000962
173Mycobacterium tuberculosis H37Rv132 Rv3408Rv3407NC_000962
174Mycobacterium tuberculosis H37Rv131 Rv3384cRv3385cNC_000962
175Mycobacterium tuberculosis H37Rv126 Rv3180cRv3181cNC_000962
176Mycobacterium vanbaalenii PYR-13287 Mvan_2940Mvan_2939NC_008726
177Mycobacterium vanbaalenii PYR-13284 Mvan_1717Mvan_1716NC_008726
178Neisseria meningitidis 0534424828 NMCC_1577NMCC_1578NC_010120
179Neisseria meningitidis FAM183326 NMC1584NMC1585NC_008767
180Neisseria meningitidis MC58406 NMB1665NMB1666NC_003112
181Nitratiruptor sp. SB155-24288 NIS_0220NIS_0219NC_009662
182Nitrobacter hamburgensis X142628 Nham_4284Nham_4285NC_007959
183Nitrobacter winogradskyi Nb-2552001 Nwi_0857Nwi_0856NC_007406
184Nitrosomonas europaea ATCC 19718905 NE1067NE1066NC_004757
185Nitrosomonas europaea ATCC 19718937 NE2112NE2111NC_004757
186Nitrosomonas eutropha C912898 Neut_0633Neut_0632NC_008344
187Nocardia farcinica IFM 101521085 nfa19600nfa19590NC_006361
188Nocardioides sp. JS6143241 Noca_3326Noca_3325NC_008699
189Nostoc punctiforme PCC 73102 (Nostoc punctiforme ATCC 29133)5470 Npun_R6079Npun_R6080NC_010628
190Nostoc punctiforme PCC 73102 (Nostoc punctiforme ATCC 29133)5461 Npun_F4200Npun_F4199NC_010628
191Nostoc punctiforme PCC 73102 (Nostoc punctiforme ATCC 29133)5457 Npun_F2723Npun_F2722NC_010628
192Nostoc punctiforme PCC 73102 (Nostoc punctiforme ATCC 29133)5449 Npun_F0372Npun_F0371NC_010628
193Nostoc sp. PCC 7120 (Anabaena sp. PCC 7120)473 all2685asl2686NC_003272
194Nostoc sp. PCC 7120 (Anabaena sp. PCC 7120)487 all4135asl4136NC_003272
195Nostoc sp. PCC 7120 (Anabaena sp. PCC 7120)469 asl2181asl2182NC_003272
196Nostoc sp. PCC 7120 (Anabaena sp. PCC 7120)481 alr3469asr3468NC_003272
197Ochrobactrum anthropi ATCC 491884336 Oant_4706Oant_4705NC_009671
198Paracoccus denitrificans PD12223205 Pden_0141Pden_0140NC_008686
199Pelodictyon phaeoclathratiforme BU-15876 Ppha_2119Ppha_2120NC_011060
200Pelodictyon phaeoclathratiforme BU-15833 Ppha_0188Ppha_0187NC_011060
201Pelodictyon phaeoclathratiforme BU-15878 Ppha_2183Ppha_2184NC_011060
202Pelotomaculum thermopropionicum SI3864 PTH_0403PTH_0402NC_009454
203Pelotomaculum thermopropionicum SI3876 PTH_2549PTH_2550NC_009454
204Polaromonas naphthalenivorans CJ23401 Pnap_3715Pnap_3716NC_008781
205Polaromonas naphthalenivorans CJ23388 Pnap_0062Pnap_0061NC_008781
206Polaromonas naphthalenivorans CJ23392 Pnap_1213Pnap_1212NC_008781
207Polaromonas naphthalenivorans CJ23395 Pnap_1823Pnap_1822NC_008781
208Polaromonas sp. JS6662573 Bpro_0013Bpro_0012NC_007948
209Prosthecochloris aestuarii DSM 2715825 Paes_1738Paes_1737NC_011059
210Pseudomonas syringae pv. phaseolicola 1448A1830 PSPPH_3343PSPPH_3342NC_005773
211Pseudomonas syringae pv. syringae B728a1873 Psyr_3418Psyr_3417NC_007005
212Pseudomonas syringae pv. tomato str. DC30001061 PSPTO_1999PSPTO_2000NC_004578
213Ralstonia eutropha JMP1341970 Reut_C6344Reut_C6345NC_007336
214Ralstonia eutropha JMP1341973 Reut_B4269Reut_B4270NC_007348
215Ralstonia solanacearum GMI1000503 RSc0871RSc0872NC_003295
216Rhizobium etli CFN 422361 RHE_PB00085RHE_PB00086NC_007763
217Rhizobium etli CIAT 6525739 RHECIAT_CH0001234RHECIAT_CH0001235NC_010994
218Rhizobium etli CIAT 6525746 RHECIAT_CH0003380RHECIAT_CH0003381NC_010994
219Rhizobium etli CIAT 6525737 RHECIAT_CH0000918RHECIAT_CH0000919NC_010994
220Rhodopseudomonas palustris BisA533001 RPE_4137RPE_4136NC_008435
221Rhodopseudomonas palustris BisA532997 RPE_3434RPE_3433NC_008435
222Rhodopseudomonas palustris BisB182527 RPC_3346RPC_3345NC_007925
223Rhodopseudomonas palustris BisB182513 RPC_1758RPC_1759NC_007925
224Rhodopseudomonas palustris BisB52621 RPD_3079RPD_3078NC_007958
225Rhodopseudomonas palustris BisB52615 RPD_1602RPD_1603NC_007958
226Rhodopseudomonas palustris CGA0091480 RPA1833RPA1834NC_005296
227Rhodopseudomonas palustris HaA22399 RPB_0355RPB_0354NC_007778
228Rhodopseudomonas palustris HaA22402 RPB_0576RPB_0575NC_007778
229Rhodopseudomonas palustris TIE-15785 Rpal_2037Rpal_2038NC_011004
230Rhodopseudomonas palustris TIE-15799 Rpal_4543Rpal_4542NC_011004
231Rhodospirillum rubrum ATCC 111702236 Rru_A0091Rru_A0090NC_007643
232Rhodospirillum rubrum ATCC 111702251 Rru_A1709Rru_A1710NC_007643
233Rickettsia akari str. Hartford4552 A1C_05140A1C_05135NC_009881
234Rickettsia bellii OSU 85-3894570 A1I_00920A1I_00925NC_009883
235Rickettsia bellii OSU 85-3894578 A1I_02270A1I_02275NC_009883
236Rickettsia bellii OSU 85-3894569 A1I_00745A1I_00740NC_009883
237Rickettsia bellii OSU 85-3894583 A1I_03750A1I_03755NC_009883
238Rickettsia bellii RML369-C2558 RBE_0981RBE_0980NC_007940
239Rickettsia bellii RML369-C2559 RBE_1021RBE_1020NC_007940
240Rickettsia bellii RML369-C2568 RBE_1361RBE_1362NC_007940
241Rickettsia bellii RML369-C2567 RBE_1244RBE_1245NC_007940
242Rickettsia canadensis str. McKiel4546 A1E_04220A1E_04215NC_009879
243Rickettsia conorii str. Malish 7356 RC0677RC0676NC_003103
244Rickettsia conorii str. Malish 7359 RC1014RC1013NC_003103
245Rickettsia conorii str. Malish 7365 RC1318RC1319NC_003103
246Rickettsia conorii str. Malish 7352 RC0379RC0380NC_003103
247Rickettsia felis URRWXCal21893 RF_0456RF_0457NC_007109
248Rickettsia felis URRWXCal21889 RF_0271RF_0272NC_007109
249Rickettsia felis URRWXCal21896 RF_0701RF_0702NC_007109
250Rickettsia felis URRWXCal21897 RF_0732RF_0731NC_007109
251Rickettsia massiliae MTU54597 RMA_1047RMA_1046NC_009900
252Rickettsia massiliae MTU54594 RMA_0390RMA_0391NC_009900
253Rickettsia massiliae MTU54598 RMA_1338RMA_1339NC_009900
254Rickettsia rickettsii str. Iowa4907 RrIowa_1206RrIowa_1205NC_010263
255Rickettsia rickettsii str. Iowa4902 RrIowa_0458RrIowa_0459NC_010263
256Rickettsia rickettsii str. Iowa4911 RrIowa_1543RrIowa_1544NC_010263
257Rickettsia rickettsii str. Sheila Smith4558 A1G_02180A1G_02185NC_009882
258Rickettsia rickettsii str. Sheila Smith4563 A1G_05595A1G_05590NC_009882
259Rickettsia rickettsii str. Sheila Smith4567 A1G_07220A1G_07225NC_009882
260Roseiflexus castenholzii DSM 139414445 Rcas_1169Rcas_1168NC_009767
261Roseiflexus castenholzii DSM 139414466 Rcas_4442Rcas_4443NC_009767
262Roseiflexus castenholzii DSM 139414460 Rcas_3687Rcas_3686NC_009767
263Roseiflexus sp. RS-14060 RoseRS_1995RoseRS_1996NC_009523
264Roseiflexus sp. RS-14049 RoseRS_0185RoseRS_0184NC_009523
265Salinispora arenicola CNS-2054710 Sare_2598Sare_2599NC_009953
266Salinispora tropica CNB-4403753 Strop_3106Strop_3107NC_009380
267Salinispora tropica CNB-4403749 Strop_2442Strop_2443NC_009380
268Serratia proteamaculans 5684523 Spro_1038Spro_1037NC_009832
269Sinorhizobium medicae WSM4194225 Smed_4694Smed_4693NC_009620
270Sinorhizobium meliloti 1021883 SMc03137SMc03136NC_003047
271Sinorhizobium meliloti 1021864 SMc00393SMc00392NC_003047
272Sphingomonas wittichii RW14010 Swit_5181Swit_5182NC_009507
273Sphingomonas wittichii RW14018 Swit_1319Swit_1318NC_009511
274Sphingomonas wittichii RW14029 Swit_4668Swit_4667NC_009511
275Synechococcus elongatus PCC 6301 (Synechococcus leopoliensis SAG)1629 syc0347_dsyc0346_dNC_006576
276Synechococcus elongatus PCC 79422193 Synpcc7942_1203Synpcc7942_1204NC_007604
277Synechococcus sp. CC93112874 sync_0198sync_0199NC_008319
278Synechococcus sp. WH 78033920 SynWH7803_1945SynWH7803_1944NC_009481
279Synechococcus sp. WH 81021270 SYNW0569SYNW0570NC_005070
280Synechocystis sp. PCC 6803977 sll0525ssl1004NC_000911
281Synechocystis sp. PCC 6803 (Synechocystis PCC6803)1808 sll5094ssl5095NC_005229
282Syntrophobacter fumaroxidans MPOB3114 Sfum_1407Sfum_1406NC_008554
283Thermoanaerobacter pseudethanolicus ATCC 332235061 Teth39_2083Teth39_2084NC_010321
284Thermoanaerobacter sp. X5145037 Teth514_0119Teth514_0118NC_010320
285Thermoanaerobacter tengcongensis MB4 (Caldanaerobacter subterraneus)766 TTE1060TTE1059NC_003869
286Thermoanaerobacter tengcongensis MB4 (Caldanaerobacter subterraneus)774 TTE2607TTE2608NC_003869
287Thermus thermophilus HB271618 TTC1804TTC1805NC_005835
288Thermus thermophilus HB271605 TTC0113TTC0114NC_005835
289Thermus thermophilus HB81846 TTHB108TTHB107NC_006462
290Thermus thermophilus HB81844 TTHB009TTHB008NC_006462
291Thermus thermophilus HB81363 TTHA0182TTHA0181NC_006461
292Thermus thermophilus HB81365 TTHA0487TTHA0488NC_006461
293Thiobacillus denitrificans ATCC 252591997 Tbd_2422Tbd_2423NC_007404
294Thiobacillus denitrificans ATCC 252591992 Tbd_0894Tbd_0895NC_007404
295Treponema denticola ATCC 354051688 TDE0465TDE0466NC_002967
296Treponema denticola ATCC 354051684 TDE0277TDE0278NC_002967
297Verminephrobacter eiseniae EF01-23460 Veis_4712Veis_4711NC_008786
298Verminephrobacter eiseniae EF01-23433 Veis_2039Veis_2040NC_008786

experimental Data derived from experimental literature


Antitoxin domain: PHD. PHD folds into an interleaved type of Zn-finger chelating 2 Zn ions in a similar manner to that of the RING and FYVE domains. Several PHD fingers have been identified as binding modules of methylated histone H3.

Toxin domain: PIN. This PIN (PilT N terminus) domain is a compact domain of about 100 amino acids. The domain has two nearly invariant aspartates. The function of the PIN domain is unknown but a role in signaling appears likely given the presence of this domain is StbB and DIS3. The majority of PIN-domain proteins found in prokaryotes are the toxic components of toxin-antitoxin operon, and toxin-antitoxin gene cassettes, though first found in plasmids, are found to be abundant in free-living prokaryotes, including many pathogenic bacteria. These loci provide a control mechanism that helps free-living prokaryotes cope with nutritional stress. In many genomes PIN domains are annotated as VapC and are part of the VapBC toxin-antitoxin operons. These operons are expanded in number in several unrelated micro-organisisms including Mycobacterium tuberculosis and Sulfolobus solfataricus.


Structure
Crystal structure of (YP_321193.1) from Anabaena variabilis ATCC 29413 at 2.00 A resolution [PDB ID: 2GA1]
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