TADB
TA Pair: Xre-YgiU
#OrganismToxinAntitoxinLocus IDReplicon
1Bordetella bronchiseptica RB501331 BB1411BB1412NC_002927
2Bordetella pertussis Tohama I1748 BP1522BP1523NC_002929
3Caldicellulosiruptor saccharolyticus DSM 89033797 Csac_2455Csac_2454NC_009437
4Candidatus Koribacter versatilis Ellin3452669 Acid345_4147Acid345_4148NC_008009
5Chlorobaculum parvum NCIB 83275812 Cpar_0602Cpar_0601NC_011027
6Chlorobium limicola DSM 2455608 Clim_1336Clim_1337NC_010803
7Chlorobium phaeobacteroides DSM 2663176 Cpha266_0072Cpha266_0071NC_008639
8Cupriavidus taiwanensis LMG 194245291 RALTA_A0165RALTA_A0166NC_010528
9Desulfitobacterium hafniense Y512481 DSY4507DSY4506NC_007907
10Desulfotomaculum reducens MI-13646 Dred_0029Dred_0030NC_009253
11Escherichia coli ATCC 87395156 EcolC_0675EcolC_0676NC_010468
12Escherichia coli HS4507 EcHS_A3200EcHS_A3199NC_009800
13Escherichia coli str. K-12 substr. DH10B5172 ECDH10B_3196ECDH10B_3195NC_010473
14Escherichia coli str. K-12 substr. MG16556100 experimental b3022b3021NC_000913
15Escherichia coli str. K-12 substr. MG16551045 experimental b3022b3021NC_000913
16Geobacter uraniireducens Rf43950 Gura_1299Gura_1300NC_009483
17Geobacter uraniireducens Rf43955 Gura_1411Gura_1410NC_009483
18Geobacter uraniireducens Rf43957 Gura_1442Gura_1441NC_009483
19Lactobacillus acidophilus NCFM1669 LBA1372LBA1371NC_006814
20Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-3653039 LBUL_1009LBUL_1010NC_008529
21Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-3653038 LBUL_0998LBUL_0997NC_008529
22Lactococcus lactis subsp. cremoris SK113034 LACR_1154LACR_1155NC_008527
23Lactococcus lactis subsp. lactis Il14031741 L198048L197116NC_002662
24Nitrobacter hamburgensis X142636 Nham_4658Nham_4657NC_007961
25Nitrosospira multiformis ATCC 251962216 Nmul_A2209Nmul_A2210NC_007614
26Pelodictyon phaeoclathratiforme BU-15867 Ppha_1841Ppha_1840NC_011060
27Pelodictyon phaeoclathratiforme BU-15827 Ppha_0058Ppha_0057NC_011060
28Polaromonas naphthalenivorans CJ23318 Pnap_4633Pnap_4634NC_008760
29Polaromonas sp. JS6662597 Bpro_5546Bpro_5547NC_007950
30Pseudomonas protegens Pf-51777 PFL_1053PFL_1052NC_004129
31Pseudomonas putida F14034 Pput_1648Pput_1649NC_009512
32Pseudomonas putida GB-15066 PputGB1_3777PputGB1_3776NC_010322
33Pseudomonas putida KT2440314 PP_4205PP_4204NC_002947
34Pseudomonas putida W6195210 PputW619_3529PputW619_3528NC_010501
35Rhodopseudomonas palustris BisA533002 RPE_4142RPE_4143NC_008435
36Syntrophus aciditrophicus SB2338 SYN_00016SYN_00015NC_007759
37Thermoanaerobacter pseudethanolicus ATCC 332235049 Teth39_0072Teth39_0073NC_010321
38Thermoanaerobacter pseudethanolicus ATCC 332235062 Teth39_2217Teth39_2216NC_010321
39Xylella fastidiosa 9a5c162 experimental XF2490XF2491NC_002488
40Xylella fastidiosa M235388 XfasM23_0362XfasM23_0363NC_010577
41Xylella fastidiosa Temecula1777 PD0370PD0371NC_004556
42Yersinia pestis Antiqua2769 YPA_0390YPA_0391NC_008150
43Yersinia pestis biovar Microtus str. 910011405 YP_3580YP_3581NC_005810
44Yersinia pestis biovar Microtus str. 910011404 YP_3580YP_3579NC_005810
45Yersinia pestis Nepal5162766 YPN_3081YPN_3080NC_008149
46Yersinia pseudotuberculosis IP 329531528 YPTB3124YPTB3123NC_006155
47Yersinia pseudotuberculosis PB1/+5483 YPTS_3248YPTS_3247NC_010634

experimental Data derived from experimental literature
T: motility quorum-sensing regulator mqsR

Antitoxin domain: Xre. Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.

Toxin domain: YgiU.


Structure
N/A
(1) Kasari V et al. (2010) The Escherichia coli mqsR and ygiT genes encode a new toxin-antitoxin pair. J Bacteriol 192(11):2908-19. [PudMed:20233923] experimental
(2) Christensen-Dalsgaard M et al. (2010) Three new RelE-homologous mRNA interferases of Escherichia coli differentiallyinduced by environmental stresses. Mol Microbiol 75(2):333-48. [PudMed:19943910] experimental
(3) Kim Y et al. (2010) Escherichia coli toxin/antitoxin pair MqsR/MqsA regulate toxin CspD. Environ Microbiol 12(5):1105-21. [PudMed:20105222] experimental
(4) Brown BL et al. (2009) Three dimensional structure of the MqsR:MqsA complex: a novel TA pair comprisedof a toxin homologous to RelE and an antitoxin with unique properties. PLoS Pathog. 5(12):e1000706. . [PudMed:20041169] 3D_structure
(5) Merfa et al. (2016) The MqsRA Toxin-Antitoxin System from Xylella fastidiosa Plays a Key Role in Bacterial Fitness, Pathogenicity, and Persister Cell Formation Front Microbiol 7:904. [PudMed:27375608] experimental
(6) Makarova KS et al. (2009) Comprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes. Biol Direct 4:19. [PudMed:19493340] in_silico