TADB
TA Pair: Xre-MazF
#OrganismToxinAntitoxinLocus IDReplicon
1Acaryochloris marina MBIC110174626 AM1_2600AM1_2601NC_009925
2Arcobacter butzleri RM40184545 Abu_1572Abu_1571NC_009850
3Candidatus Desulforudis audaxviator MP104C5129 Daud_0402Daud_0403NC_010424
4Cyanothece sp. ATCC 511425343 cce_3905cce_3904NC_010546
5Geobacter uraniireducens Rf43989 Gura_3814Gura_3815NC_009483
6Gloeobacter violaceus PCC 74211409 glr0126gsr0125NC_005125
7Methylobacterium populi BJ0015571 Mpop_4047Mpop_4046NC_010725
8Microcystis aeruginosa NIES-8434945 MAE_08750MAE_08740NC_010296
9Microcystis aeruginosa NIES-8434976 MAE_24660MAE_24670NC_010296
10Nostoc sp. PCC 7120 (Anabaena sp. PCC 7120)459 alr0758asr0757NC_003272
11Nostoc sp. PCC 7120 (Anabaena sp. PCC 7120)478 asr3006asr3005NC_003272
12Roseiflexus castenholzii DSM 139414448 Rcas_1516Rcas_1517NC_009767
13Streptococcus pyogenes M1 GAS746 SPy_0938SPy_0939NC_002737
14Streptococcus pyogenes MGAS61801945 M28_Spy1031M28_Spy1030NC_007296
15Streptococcus pyogenes MGAS8232999 spyM18_1307spyM18_1306NC_003485
16Thermoanaerobacter pseudethanolicus ATCC 332235060 Teth39_1905Teth39_1906NC_010321
17Thermoanaerobacter sp. X5145038 Teth514_0295Teth514_0294NC_010320
18Trichodesmium erythraeum IMS1012867 Tery_1071Tery_1072NC_008312


Antitoxin domain: Xre. Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.

Toxin domain: MazF. Growth inhibitor [Signal transduction mechanisms]


Structure
A Conserved Mode Of Protein Recognition And Binding In A ParD-ParE Toxin-Antitoxin Complex. [PDB ID: 3KXE] [PudMed:20143871]
(1) Makarova KS et al. (2009) Comprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotes. Biol Direct 4:19. [PudMed:19493340] in_silico