TADB
Mycobacterium tuberculosis H37Rv complete genome. chromosome

# GENOME INFO
Genome size (bp) : 4411532
Link to NCBI Taxonomy Browser by Tax_id :83332
 
# TA INFO in replicon: NC_000962
#TypeToxinAntitoxinRegulatorLocationClassification(family/domain)
1 2 Rv0059 Rv0060 - 63200..64967 -/-
2 experimental 2 Rv0065 Rv0064A - 71589..72222 vapBC */RHH-PIN
3 2 Rv0240 Rv0239 - 289104..289782 vapBC */RHH-PIN
4 experimental 2 Rv0299 Rv0298 - 363252..363778 mazEF, ccd or relBE */RHH-MazF
5 experimental 2 Rv0301 Rv0300 - 363826..364469 vapBC/RHH-PIN
6 2 Rv0456a Rv0456B - 547076..547517 -/RHH-PIN(toxin)
7 2 Rv0549c Rv0550c - 640228..640904 vapBC/RHH-PIN
8 2 Rv0582 Rv0581 - 677710..678329 vapBC */RHH-PIN
9 experimental 2 Rv0595c Rv0596c - 694839..695485 vapBC/PHD-PIN
10 experimental 2 Rv0598c Rv0599c - 697154..697800 vapBC/AbrB-PIN
11 experimental 2 Rv0609 Rv0608 - 703244..703887 vapBC/RHH-PIN
12 2 Rv0617 Rv0616c - 710584..711407 vapBC/-
13 2 Rv0624 Rv0623 - 716410..717059 vapBC/RHH-PIN
14 experimental 2 Rv0627 Rv0626 - 718025..718689 vapBC/PHD-PIN
15 experimental 2 Rv0656c Rv0657c - 752984..753617 vapBC/RHH-PIN
16 experimental 2 Rv0659c Rv0660c - 754685..755225 mazEF/RHH-MazF
17 experimental 2 Rv0661c Rv0662c - 755335..756137 vapBC/RHH-PIN
18 experimental 2 Rv0665 Rv0664 - 758532..759139 vapBC/-
19 experimental 2 Rv0749 Rv0748 - 840947..841656 vapBC/RHH-PIN
20 2 Rv0836c Rv0837c - 932279..934031 -/-
21 2 Rv0910 Rv0909 - 1014681..1015300 unclassified/-
22 2 Rv0919 Rv0918 - 1024211..1025184 -/RHH-GNAT
23 2 Rv0960 Rv0959A - 1073327..1073928 -/-
24 experimental 2 Rv1102c Rv1103c - 1230660..1231291 mazEF/-
25 2 Rv1114 Rv1113 - 1239416..1239984 vapBC/RHH-PIN
26 2 Rv1242 Rv1241 - 1384278..1384966 vapBC/RHH-PIN
27 experimental 2 Rv1246c Rv1247c - 1388685..1389244 relBE/PHD-RelE
28 experimental 2 Rv1397c Rv1398c - 1574112..1574767 vapBC/RHH-PIN
29 2 Rv1495 Rv1494 - 1686271..1686887 mazEF/-
30 2 Rv1546 Rv1545 - 1746919..1747626 unclassified/-
31 experimental 2 Rv1561 Rv1560 - 1764755..1765383 vapBC/RHH-PIN
32 2 Rv1720c Rv1721c - 1947030..1947643 vapBC */RHH-PIN
33 2 Rv1741 Rv1740 - 1967705..1968165 vapBC/RHH-PIN
34 2 Rv1838c Rv1839c - 2087257..2087912 vapBC/RHH-PIN
35 experimental 2 Rv1942c Rv1943c - 2194644..2195347 mazEF/-
36 2 Rv1953 Rv1952 - 2200726..2201249 vapBC/RHH-PIN
37 experimental 2 Rv1955 Rv1956 - 2201584..2202587 higBA/Xre-RelE
38 experimental 2 Rv1959c Rv1960c - 2203681..2204225 parDE/RHH-RelE
39 experimental 2 Rv1962c Rv1963c - 2204866..2206802 -/RHH-RelE(toxin)
40 experimental 2 Rv1982c Rv1982a - 2225413..2226101 vapBC */RHH-PIN
41 2 Rv1989c Rv1990c - 2232739..2233637 -/COG5642-COG5654
42 experimental 2 Rv1991c Rv1991a - 2234305..2234891 mazEF, ccd or relBE */RHH-MazF
43 experimental 2 Rv2010 Rv2009 - 2258030..2258671 vapBC/RHH-PIN
44 2 Rv2019 Rv2018 - 2265280..2266405 -/COG2442-PIN
45 2 Rv2022c Rv2021c - 2266805..2267724 relBE */Xre-RelE
46 2 Rv2035 Rv2034 - 2281294..2282102 -/ArsR-COG3832
47 2 Rv2063A Rv2063 - 2320831..2321467 mazEF, ccd or relBE */RHH-MazF
48 experimental 2 Rv2103c Rv2104c - 2364086..2364781 vapBC/RHH-PIN
49 experimental 2 Rv2142c Rv2142A - 2402193..2402722 -/-
50 2 Rv2231A Rv2231B - 2505736..2506383 vapBC */PHD-PIN
51 2 Rv2274c Rv2274A - 2546488..2547087 -/PHD-PIN(toxin)
52 experimental 2 Rv2494 Rv2493 - 2808083..2808735 vapBC/RHH-PIN
53 2 Rv2527 Rv2526 - 2851091..2851716 vapBC/RHH-PIN
54 2 Rv2530c Rv2530A - 2854267..2854907 vapBC/RHH-PIN
55 2 Rv2546 Rv2545 - 2867783..2868567 vapBC/RHH-PIN
56 2 Rv2548 Rv2547 - 2868606..2869237 vapBC/RHH-PIN
57 experimental 2 Rv2549c Rv2550c - 2869727..2870364 vapBC/RHH-PIN
58 2 Rv2596 Rv2595 - 2925492..2926138 vapBC/AbrB-PIN
59 2 Rv2602 Rv2601A - 2930070..2930784 vapBC/RHH-PIN
60 2 Rv2653c Rv2654c - 2976586..2977234 unclassified/-
61 2 Rv2697c Rv3697A - 3013683..4140463 -/RHH-PIN(antitoxin)
62 2 Rv2757c Rv2758c - 3070170..3070849 vapBC/RHH-PIN
63 2 Rv2759c Rv2760c - 3070875..3071536 vapBC/RHH-PIN
64 experimental 2 Rv2801c Rv2801A - 3110167..3110737 mazEF, ccd or relBE */RHH-MazF
65 2 Rv2829c Rv2830c - 3136620..3137224 vapBC/PHD-PIN
66 2 Rv2863 Rv2862A - 3174747..3175372 -/-
67 experimental 2 Rv2866 Rv2865 - 3177537..3178085 relBE/PHD-RelE
68 experimental 2 Rv2872 Rv2871 - 3183138..3183825 vapBC/RHH-PIN
69 2 Rv3180c Rv3181c - 3549254..3550143 vapBC */PHD-PIN
70 2 Rv3182 Rv3183 - 3550374..3551044 relBE */Xre-RelE
71 2 Rv3189 Rv3188 - 3554298..3555262 -/Xre-COG5654
72 experimental 2 Rv3320c Rv3321c - 3707642..3708316 vapBC/RHH-PIN
73 experimental 2 Rv3358 Rv3357 - 3770773..3771302 relBE/PHD-RelE
74 2 Rv3384c Rv3385c - 3799243..3799943 vapBC/PHD-PIN
75 2 Rv3408 Rv3407 - 3826252..3826958 vapBC/PHD-PIN
76 2 Rv3749c Rv3750c - 4197628..4198597 -/MerR-PIN

experimental TA derived from experimental literature

: TA pair identified by RASTA-Bacteria .
- : unclassified

The further putative TA pairs predicted by RASTA-Bacteria .
#ToxinDomain1Score1AntitoxinDomain2Score2Replicon
1Rv1960cCOG360988.69Rv1959cPlasmid_stabil/ParE92.63NC_000962
2Rv1103cCOG3609/HTH_483.47Rv1102cPemK/MazF88.14NC_000962
3Rv1398cHTH_487.15Rv1397cVapC/PIN/COG184887.18NC_000962
4Rv2547HTH_486.05Rv2548VapC/PIN/COG184886.81NC_000962
5Rv2547HTH_486.05Rv2546VapC/PIN86.5NC_000962
6Rv0661cCOG1848/PIN84.22Rv0662cHTH_486.47NC_000962
7Rv0300HTH_483.65Rv0301VapC/PIN/COG184885.16NC_000962
8Rv2871HTH_463.14Rv2872COG1848/PIN84.16NC_000962
9Rv2515cHTH_3/HTH_XRE/HTH_XRE/HipB63.05Rv2514cVapC/PIN83.69NC_000962
10Rv1494-61Rv1495PemK/MazF76.27NC_000962
11Rv1943c-60.58Rv1942cPemK/MazF75.18NC_000962
12Rv2009-60.97Rv2010PIN/VapC/COG184874.85NC_000962
13Rv2526-64.87Rv2527VapC/PIN74.75NC_000962
14Rv1721c-62.68Rv1720cCOG4113/PIN74.13NC_000962
15Rv1560-63.81Rv1561PIN/VapC/COG184873.74NC_000962
16Rv1839c-67.68Rv1838cCOG1848/PIN73.62NC_000962
17Rv0660c-65Rv0659cPemK/MazF73.6NC_000962
18Rv1113-67.1Rv1114VapC/PIN/COG184873.44NC_000962
19Rv2758c-63.06Rv2757cVapC/PIN/COG184873.22NC_000962
20Rv0666-67.1Rv0665VapC/PIN73.03NC_000962
21Rv2020c-62.64Rv2021cHTH_XRE/HTH_XRE/HTH_3/HipB72.56NC_000962
22Rv2104c-67.97Rv2103cCOG1848/PIN/VapC71.52NC_000962
23Rv0239-67.16Rv0240COG1848/PIN71.27NC_000962
24Rv1241-64.13Rv1242COG1848/PIN70.73NC_000962
25Rv2493-64.19Rv2494COG184870.6NC_000962
Note: The RASTA-Bacteria algorithm utilises rpsblast search and typical characteristics of TA loci, such as a two-gene, co-directed module coding for small proteins, to identify TA hits. RASTA-Bacteria TA pair hits with one score >70% and the other > 60% were recorded by TADB, this strict cut-off yields broadly reliable TA candidates.