TADB
Streptococcus pyogenes MGAS6180 chromosome, complete genome. chromosome

# GENOME INFO
Genome size (bp) : 1897573
Link to NCBI Taxonomy Browser by Tax_id :319701
 
# TA INFO in replicon: NC_007296
#TypeToxinAntitoxinRegulatorLocationClassification(family/domain)
1 2 M28_Spy0445 M28_Spy0444 - 452878..453512 RelBE or parDE */RHH-RelE
2 2 M28_Spy1031 M28_Spy1030 - 1029438..1031003 mazEF */Xre-MazF
3 2 M28_Spy1283 M28_Spy1282 - 1266570..1267323 -/Xre-COG2856
4 2 M28_Spy1331 M28_Spy1330 - 1313889..1314704 -/Xre-COG2856
5 2 M28_Spy1333 M28_Spy1334 - 1315128..1315756 mazEF, ccd or relBE */RHH-MazF
6 2 M28_Spy1631 M28_Spy1630 - 1634294..1634855 RelBE or parDE */RHH-RelE
7 2 M28_Spy1840 M28_Spy1841 - 1846059..1846590 RelBE or parDE */RHH-RelE

: TA pair identified by RASTA-Bacteria .
* : TA family predicted based on the TA domain pair using the relationship in Table S2

The further putative TA pairs predicted by RASTA-Bacteria .
#ToxinDomain1Score1AntitoxinDomain2Score2Replicon
1M28_Spy0445ParE/Plasmid_stabil/RelE89.98M28_Spy0446-68.39NC_007296
2M28_Spy1793HTH_XRE/HTH_XRE/HTH_385.16M28_Spy1794-64NC_007296
3M28_Spy1841-68.39M28_Spy1840RelE79.98NC_007296
4M28_Spy1793HTH_XRE/HTH_XRE/HTH_385.16M28_Spy1792HTH_XRE/HTH_XRE/HTH_3/HipB91.06NC_007296
5M28_Spy1546-64.32M28_Spy1545HTH_XRE/HTH_XRE/HTH_3/HipB72.79NC_007296
Note: The RASTA-Bacteria algorithm utilises rpsblast search and typical characteristics of TA loci, such as a two-gene, co-directed module coding for small proteins, to identify TA hits. RASTA-Bacteria TA pair hits with one score >70% and the other > 60% were recorded by TADB, this strict cut-off yields broadly reliable TA candidates.