TADB
Streptococcus pyogenes MGAS9429 chromosome, complete genome. chromosome

# GENOME INFO
Genome size (bp) : 1836467
Link to NCBI Taxonomy Browser by Tax_id :370551
 
# TA INFO in replicon: NC_008021
#TypeToxinAntitoxinRegulatorLocationClassification(family/domain)
1 2 MGAS9429_Spy0456 MGAS9429_Spy0455 - 453345..453979 RelBE or parDE */RHH-RelE
2 2 MGAS9429_Spy0565 MGAS9429_Spy0564 - 546708..547403 hicBA */HicB-HicA
3 2 MGAS9429_Spy0799 MGAS9429_Spy0798 - 782213..783291 -/Xre-Bro
4 2 MGAS9429_Spy1467 MGAS9429_Spy1466 - 1417857..1418655 -/Xre-COG2856
5 2 MGAS9429_Spy1644 MGAS9429_Spy1643 - 1597558..1598170 RelBE or parDE */RHH-RelE

: TA pair identified by RASTA-Bacteria .
* : TA family predicted based on the TA domain pair using the relationship in Table S2

The further putative TA pairs predicted by RASTA-Bacteria .
#ToxinDomain1Score1AntitoxinDomain2Score2Replicon
1MGAS9429_Spy0456ParE/Plasmid_stabil/RelE89.98MGAS9429_Spy0457-68.39NC_008021
2MGAS9429_Spy0564COG159882.74MGAS9429_Spy0565COG172488.13NC_008021
3MGAS9429_Spy0451-60.58MGAS9429_Spy0450HTH_XRE/HTH_XRE/HTH_3/HipB78.3NC_008021
4MGAS9429_Spy1643RelB85.8MGAS9429_Spy1644ParE86.34NC_008021
Note: The RASTA-Bacteria algorithm utilises rpsblast search and typical characteristics of TA loci, such as a two-gene, co-directed module coding for small proteins, to identify TA hits. RASTA-Bacteria TA pair hits with one score >70% and the other > 60% were recorded by TADB, this strict cut-off yields broadly reliable TA candidates.