TADB
Streptococcus pyogenes MGAS10270 chromosome, complete genome. chromosome

# GENOME INFO
Genome size (bp) : 1928252
Link to NCBI Taxonomy Browser by Tax_id :370552
 
# TA INFO in replicon: NC_008022
#TypeToxinAntitoxinRegulatorLocationClassification(family/domain)
1 2 MGAS10270_Spy0458 MGAS10270_Spy0456 - 452335..452996 RelBE or parDE */RHH-RelE
2 2 MGAS10270_Spy0548 MGAS10270_Spy0549 - 535283..536446 -/-
3 2 MGAS10270_Spy0569 MGAS10270_Spy0568 - 547985..548599 hicBA */HicB-HicA
4 2 MGAS10270_Spy0800 MGAS10270_Spy0801 - 775171..775891 -/Xre-COG2856
5 2 MGAS10270_Spy1346 MGAS10270_Spy1347 - 1288597..1289376 -/-
6 2 MGAS10270_Spy1359 MGAS10270_Spy1358 - 1293668..1294421 -/Xre-COG2856
7 2 MGAS10270_Spy1405 MGAS10270_Spy1404 - 1339790..1340605 -/Xre-COG2856
8 2 MGAS10270_Spy1407 MGAS10270_Spy1408 - 1341029..1341657 mazEF, ccd or relBE */RHH-MazF
9 2 MGAS10270_Spy1710 MGAS10270_Spy1709 - 1659702..1660314 RelBE or parDE */RHH-RelE
10 2 MGAS10270_Spy1927 MGAS10270_Spy1928 - 1876669..1877200 RelBE or parDE */RHH-RelE

: TA pair identified by RASTA-Bacteria .
* : TA family predicted based on the TA domain pair using the relationship in Table S2

The further putative TA pairs predicted by RASTA-Bacteria .
#ToxinDomain1Score1AntitoxinDomain2Score2Replicon
1MGAS10270_Spy1878HTH_XRE/HTH_XRE/HTH_385.16MGAS10270_Spy1877HTH_XRE/HTH_XRE/HTH_3/HipB91.06NC_008022
2MGAS10270_Spy0546-60.74MGAS10270_Spy0547HTH_XRE/HTH_XRE/HTH_3/HipB/VapI75.72NC_008022
3MGAS10270_Spy0568COG159882.74MGAS10270_Spy0569COG172488.13NC_008022
4MGAS10270_Spy1709RelB85.8MGAS10270_Spy1710ParE87.14NC_008022
5MGAS10270_Spy0453-60.58MGAS10270_Spy0452HTH_XRE/HTH_XRE/HTH_3/HipB78.3NC_008022
6MGAS10270_Spy1928-68.39MGAS10270_Spy1927RelE79.98NC_008022
7MGAS10270_Spy1710ParE87.14MGAS10270_Spy1711-65NC_008022
8MGAS10270_Spy1878HTH_XRE/HTH_XRE/HTH_385.16MGAS10270_Spy1879-64NC_008022
Note: The RASTA-Bacteria algorithm utilises rpsblast search and typical characteristics of TA loci, such as a two-gene, co-directed module coding for small proteins, to identify TA hits. RASTA-Bacteria TA pair hits with one score >70% and the other > 60% were recorded by TADB, this strict cut-off yields broadly reliable TA candidates.