TADB
Streptococcus pyogenes str. Manfredo chromosome, complete genome. chromosome

# GENOME INFO
Genome size (bp) : 1841271
Link to NCBI Taxonomy Browser by Tax_id :160491
 
# TA INFO in replicon: NC_009332
#TypeToxinAntitoxinRegulatorLocationClassification(family/domain)
1 2 SpyM50473 SpyM50474 - 515952..516663 -/Xre-COG2856
2 2 SpyM50476 SpyM50475 - 516846..517820 -/Xre-Bro
3 2 SpyM50633 SpyM50634 - 656069..656808 -/Xre-COG2856
4 2 SpyM51068 SpyM51067 - 1067565..1068304 -/Xre-COG2856
5 2 SpyM51292 SpyM51293 - 1293369..1293983 hicBA */HicB-HicA
6 2 SpyM51316 SpyM51317 - 1305049..1306047 -/Xre-Bro
7 2 SpyM51406 SpyM51407 - 1390614..1391221 RelBE or parDE */RHH-RelE
8 2 SpyM51616 SpyM51615 - 1598866..1599478 RelBE or parDE */RHH-RelE

: TA pair identified by RASTA-Bacteria .
* : TA family predicted based on the TA domain pair using the relationship in Table S2

The further putative TA pairs predicted by RASTA-Bacteria .
#ToxinDomain1Score1AntitoxinDomain2Score2Replicon
1SpyM51406ParE/Plasmid_stabil90.08SpyM51405-68.39NC_009332
2SpyM51293COG159882.74SpyM51292COG172488.13NC_009332
3SpyM51615RelB85.87SpyM51616ParE86.44NC_009332
Note: The RASTA-Bacteria algorithm utilises rpsblast search and typical characteristics of TA loci, such as a two-gene, co-directed module coding for small proteins, to identify TA hits. RASTA-Bacteria TA pair hits with one score >70% and the other > 60% were recorded by TADB, this strict cut-off yields broadly reliable TA candidates.