TADB
TADB 2.0: an updated database of bacterial type II toxin-antitoxin loci

 
Toxin-antitoxin (TA) loci play a role in bacterial stress physiology and the stabilisation of horizontally acquired elements. TA loci are found abundantly distributed among free-living Bacteria and Archaea. TA loci code for a stable toxin that is neutralized by a short-lived antitoxin. The antitoxin can be either an antisense RNA (Type 1 TA loci) or a protein (Type 2 TA loci). To date, six type TA systems have been reported (see the recent review of Rebecca Page & Wolfgang PetiNature in Chemical Biology 2016, 12, 208–214). The aim of this PostgreSQL-based TADB database is to create and maintain a resource of all currently available type II TA loci-relevant data ranging from 'wet' experimental data to information garnered by bioinformatics analyses.

Reference for TADB 2.0: Y. Xie, Y. Wei, Y. Shen, X. Li, H. Zhou, C. Tai, Z. Deng and H.Y. Ou (2018) TADB 2.0: an updated database of bacterial type II toxin-antitoxin loci. Nucleic Acids Research, Database issue.

Reference for TADB 1.0: Y. Shao, E.M. Harrison, D. Bi, C. Tai, X. He, H.Y. Ou, K. Rajakumar and Z. Deng (2011) TADB: a web-based resource for Type 2 toxin-antitoxin loci in Bacteria and Archaea. Nucleic Acids Research, 39, D606-D611. [Abstract]

Current version: 2.0
Since Dec., 2010; Updated: Oct., 2017
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